| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4229834 | B | Displacement of [3H]-ketanserin from human 5-HT2AR expressed in CHO-K1 cell membranes after 1.5 hrs by microbeta counting method | Homo sapiens | 51 | cell-based format | Scientific Literature | ||
| 2. | ALA4229835 | B | Displacement of [3H]-LSD from human 5-HT6R expressed in HEK293 cell membranes after 1 hr at 37 degC by microbeta counting method | Homo sapiens | 51 | cell-based format | Scientific Literature | ||
| 3. | ALA4229836 | B | Displacement of [3H]-8-OH-DPAT from human 5-HT1AR expressed in HEK293 cell membranes after 1 hr by microbeta counting method | Homo sapiens | 51 | cell-based format | Scientific Literature | ||
| 4. | ALA4229837 | B | Displacement of [3H]-5-CT from human 5-HT7R expressed in HEK293 cell membranes after 1 hr at 37 degC by microbeta counting method | Homo sapiens | 51 | cell-based format | Scientific Literature | ||
| 5. | ALA4229838 | B | Displacement of [3H]-raclopride from human D2LR expressed in HEK293 cell membranes after 1 hr at 37 degC by microbeta counting method | Homo sapiens | 51 | cell-based format | Scientific Literature | ||
| 6. | ALA4229839 | B | Selectivity index, ratio of pKi for 5-HT2AR to pKi for human D2LR | Homo sapiens | 51 | assay format | Scientific Literature | ||
| 7. | ALA4229840 | F | Partial agonist activity at human 5-HT1AR expressed in CHO-K1 cells assessed as increase in cAMP accumulation by chemiluminescence-based assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4229841 | F | Partial agonist activity at human 5-HT1AR expressed in CHO-K1 cells assessed as increase in cAMP accumulation at 10'-6 M by chemiluminescence-based assay relative to serotonin | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4229844 | F | Antagonist activity at human 5-HT2AR expressed in HEK293 cells assessed as inhibition of serotonin-induced IP1 accumulation by chemiluminescence-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4229845 | F | Antagonist activity at human 5-HT2AR expressed in HEK293 cells assessed as inhibition of serotonin-induced IP1 accumulation at 10'-6 M by chemiluminescence-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4229847 | F | Antagonist activity at human 5-HT1AR expressed in mouse BA/F3 cells assessed as inhibition of serotonin-induced calcium flux at 10'-6 M by fluorimetric method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4229848 | F | Antagonist activity at human 5-HT1AR expressed in CHO-K1 cells assessed as inhibition of serotonin-induced cAMP accumulation by chemiluminescence-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4229849 | F | Antagonist activity at human 5-HT1AR expressed in CHO-K1 cells assessed as inhibition of serotonin-induced cAMP accumulation at 10'-6 M by chemiluminescence-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4229852 | F | Antagonist activity at human 5-HT6R expressed in CHO-K1 cells assessed as inhibition of serotonin-induced cAMP accumulation by chemiluminescence-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4229853 | F | Antagonist activity at human 5-HT6R expressed in CHO-K1 cells assessed as inhibition of serotonin-induced cAMP accumulation at 10'-6 M by chemiluminescence-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4229856 | F | Antagonist activity at human 5-HT7R expressed in human DLD1 cells assessed as inhibition of serotonin-induced cAMP accumulation by chemiluminescence-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4229857 | F | Antagonist activity at human 5-HT7R expressed in human DLD1 cells assessed as inhibition of serotonin-induced cAMP accumulation at 10'-6 M by chemiluminescence-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4229860 | F | Antagonist activity at human D2LR expressed in CHO-K1 cells assessed as inhibition of dopamine-induced cAMP accumulation by chemiluminescence-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4229861 | F | Antagonist activity at human D2LR expressed in CHO-K1 cells assessed as inhibition of dopamine-induced cAMP accumulation at 10'-6 M by chemiluminescence-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4229864 | F | Antagonist activity at human D3R expressed in CHO-K1 cells assessed as inhibition of serotonin-induced cAMP accumulation by chemiluminescence-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!