| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4232623 | B | Inhibition of SAH-rhodamine binding to NNMT in human 786-O cell soluble proteomic lysate at 0.5 to 2 uM preincubated for 1 hr followed by SAH-rhodamine addition measured after 5 mins by Gel-based ABPP analysis | Homo sapiens | 38 | ALA4229400 | assay format | Scientific Literature | |
| 2. | ALA4232624 | B | Inhibition of SAH-rhodamine binding to NNMT in human 786-O cell soluble proteomic lysate preincubated for 1 hr followed by SAH-rhodamine addition measured after 5 mins by Gel-based ABPP analysis | Homo sapiens | 11 | ALA4229400 | assay format | Scientific Literature | |
| 3. | ALA4232625 | B | Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate preincubated for 1 hr followed by substrate and SAM addition measured after 15 to 30 mins by LC-MS analysis | Homo sapiens | 3 | ALA4229400 | assay format | Scientific Literature | |
| 4. | ALA4232626 | B | Inhibition of NNMT C165A mutant in human 786-O cell lysate using d4-nicotinamide as substrate preincubated for 1 hr followed by substrate and SAM addition measured after 15 to 30 mins by LC-MS analysis | Homo sapiens | 2 | ALA4229400 | assay format | Scientific Literature | |
| 5. | ALA4232627 | B | Inhibition of SAH-rhodamine binding to NNMT in human 786-O cell soluble proteomic lysate assessed as ratio of observed rate constant to test compound concentration preincubated for 10 to 40 mins followed by SAH-rhodamine addition measured after 5 mins by Gel-based ABPP analysis | Homo sapiens | 2 | ALA4229400 | assay format | Scientific Literature | |
| 6. | ALA4232628 | B | Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate pretreated for 1 hr at 3 mins post 160 uM SAM addition followed by substrate addition measured after 15 to 30 mins by LC-MS analysis | Homo sapiens | 1 | ALA4229400 | assay format | Scientific Literature | |
| 7. | ALA4232629 | B | Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate pretreated for 1 hr at 3 mins post 80 uM SAM addition followed by substrate addition measured after 15 to 30 mins by LC-MS analysis | Homo sapiens | 1 | ALA4229400 | assay format | Scientific Literature | |
| 8. | ALA4232630 | B | Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate pretreated for 1 hr at 3 mins post 40 uM SAM addition followed by substrate addition measured after 15 to 30 mins by LC-MS analysis | Homo sapiens | 1 | ALA4229400 | assay format | Scientific Literature | |
| 9. | ALA4232631 | B | Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate pretreated for 1 hr at 3 mins post 20 uM SAM addition followed by substrate addition measured after 15 to 30 mins by LC-MS analysis | Homo sapiens | 1 | ALA4229400 | assay format | Scientific Literature | |
| 10. | ALA4232632 | B | Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate pretreated for 1 hr at 3 mins post 10 uM SAM addition followed by substrate addition measured after 15 to 30 mins by LC-MS analysis | Homo sapiens | 1 | ALA4229400 | assay format | Scientific Literature | |
| 11. | ALA4232633 | B | Binding affinity to NNMT C165 residue in human 786-O cell lysate at 5 uM incubated for 4 hrs followed by cell lysis by IA-alkyne probe based isoTOP-ABPP analysis | Homo sapiens | 2 | ALA4229400 | assay format | Scientific Literature | |
| 12. | ALA4232634 | B | Binding affinity to NNMT C165 residue in human 786-O cell soluble proteomic lysate at 1 to 5 uM incubated for 1 hr followed by cell lysis by IA-alkyne probe based isoTOP-ABPP analysis | Homo sapiens | 2 | ALA4229400 | assay format | Scientific Literature | |
| 13. | ALA4232636 | B | Binding affinity to HMOX2 cysteine residue in human 786-O cell soluble proteomic lysate at 5 uM incubated for 1 hr followed by cell lysis by IA-alkyne probe based isoTOP-ABPP analysis | Homo sapiens | 3 | ALA4229400 | assay format | Scientific Literature | |
| 14. | ALA4232637 | B | Binding affinity to ALDH1A1 cysteine residue in human 786-O cell soluble proteomic lysate at 5 uM incubated for 1 hr followed by cell lysis by IA-alkyne probe based isoTOP-ABPP analysis | Homo sapiens | 2 | ALA4229400 | assay format | Scientific Literature | |
| 15. | ALA4232641 | B | Binding affinity to GSTO1 cysteine residue in human 786-O cell soluble proteomic lysate at 5 uM incubated for 1 hr followed by cell lysis by IA-alkyne probe based isoTOP-ABPP analysis | Homo sapiens | 2 | ALA4229400 | assay format | Scientific Literature | |
| 16. | ALA4232642 | B | Binding affinity to CKAP4 cysteine residue in human 786-O cell soluble proteomic lysate at 5 uM incubated for 1 hr followed by cell lysis by IA-alkyne probe based isoTOP-ABPP analysis | Homo sapiens | 2 | ALA4229400 | assay format | Scientific Literature | |
| 17. | ALA4232643 | B | Binding affinity to REEP5 cysteine residue in human 786-O cell soluble proteomic lysate at 5 uM incubated for 1 hr followed by cell lysis by IA-alkyne probe based isoTOP-ABPP analysis | Homo sapiens | 1 | ALA4229400 | assay format | Scientific Literature | |
| 18. | ALA4232644 | B | Binding affinity to TXNDC17 cysteine residue in human 786-O cell soluble proteomic lysate at 5 uM incubated for 1 hr followed by cell lysis by IA-alkyne probe based isoTOP-ABPP analysis | Homo sapiens | 1 | ALA4229400 | assay format | Scientific Literature | |
| 19. | ALA4232649 | B | Binding affinity to GSTO1 C32 residue in human 786-O cell lysate at 5 uM incubated for 1 hr followed by cell lysis by IA-alkyne probe based isoTOP-ABPP analysis | Homo sapiens | 1 | ALA4229400 | assay format | Scientific Literature | |
| 20. | ALA4232650 | B | Binding affinity to HMOX2 cysteine residue in human 786-O cell lysate at 5 uM incubated for 1 hr followed by cell lysis by IA-alkyne probe based isoTOP-ABPP analysis | Homo sapiens | 1 | ALA4229400 | assay format | Scientific Literature |
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