# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4237076 | F | Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as inhibition of RANTES-induced calcium flux preincubated for 10 mins followed by RANTES addition by fluo-4AM-based fluorescence assay | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
2. | ALA5154013 | F | Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for 15 mins by Fluo-4 AM calcium flux assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
3. | ALA5154014 | F | Antiviral activity against HIV-1 Ba-L infected in human TZM-bl cells measured after 48 hrs incubation by luciferase based analysis | Human immunodeficiency virus 1 | 16 | organism-based format | Scientific Literature | ||
4. | ALA5154015 | T | Cytotoxicity against human TZM-bl cells incubated for 48 hrs by MTT assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
5. | ALA5154016 | T | Therapeutic index, ratio of CC50 for human TZM-bl cells to EC50 for antiviral activity against HIV-1 Ba-L | 15 | assay format | Scientific Literature |