# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4231332 | Functional | Trypanocidal activity against Trypanosoma brucei gambiense FeoITMAP/1893 after 72 hrs by resazurin dye based assay | Trypanosoma brucei gambiense | 24 | ALA4229356 | organism-based format | Scientific Literature | |
2. | ALA4231333 | Toxicity | Selectivity index, ratio of CC50 for mouse RAW264.7 cells to IC50 for Trypanosoma brucei gambiense FeoITMAP/1893 | 23 | ALA4229356 | assay format | Scientific Literature | ||
3. | ALA4231334 | Functional | Antiparasitic activity against Leishmania donovani LV9 axenic amastigotes incubated for 72 hrs by resazurin dye based assay | Leishmania donovani | 24 | ALA4229356 | organism-based format | Scientific Literature | |
4. | ALA4231336 | Functional | Antiparasitic activity against Leishmania donovani LV9 axenic intramacrophage amastigotes infected in mouse RAW264.7 cells incubated for 48 hrs by Sybr Green 1 dye based fluorescence assay | Leishmania donovani | 24 | ALA4229356 | organism-based format | Scientific Literature | |
5. | ALA4231338 | ADME | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability after 48 hrs by resazurin assay | Mus musculus | 24 | ALA4229356 | cell-based format | Scientific Literature | |
6. | ALA4231340 | Binding | Inhibition of Trypanosoma brucei trypanothione reductase at 40 uM using 40 uM TS2 as substrate in presence of NADPH by spectrophotometric method relative to control | Trypanosoma brucei | 4 | ALA4229356 | single protein format | Scientific Literature | |
7. | ALA4231341 | Binding | Inhibition of Trypanosoma brucei trypanothione reductase at 40 uM using 100 uM TS2 as substrate in presence of NADPH by spectrophotometric method relative to control | Trypanosoma brucei | 2 | ALA4229356 | single protein format | Scientific Literature |