# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4233799 | B | Inhibition of rat liver microsomes 5alpha-reductase1 using [1,2,6,7-3H]T as substrate measured after 60 mins by chromatographic method | Rattus norvegicus | 7 | ALA4229445 | microsome format | Scientific Literature | |
2. | ALA4233800 | F | Inhibition of testosterone-induced flank organ enlargement in golden hamster assessed as reduction in diameter of pigmented spot at 2 mg/kg, sc administered daily for 6 days measured post last dose by calliper method | Mesocricetus auratus | 6 | ALA4229445 | organism-based format | Scientific Literature | |
3. | ALA4233803 | F | Inhibition of testosterone-induced increase in prostate weight in golden hamster at 2 mg/kg, sc administered daily for 6 days measured post last dose | Mesocricetus auratus | 7 | ALA4229445 | organism-based format | Scientific Literature | |
4. | ALA4233804 | F | Inhibition of testosterone-induced increase in seminal vesicle weight in golden hamster at 2 mg/kg, sc administered daily for 6 days measured post last dose | Mesocricetus auratus | 7 | ALA4229445 | organism-based format | Scientific Literature | |
5. | ALA4233805 | A | Drug metabolism in golden hamster plasma assessed as esterase-mediated 21(2-Oxo-ethyl-benzimidazol)-3-ceto, pregnen-16,17-diene formation by measuring retardation factor at 4 mg/kg, sc measured after 30 mins in presence of testosterone by TLC method | Mesocricetus auratus | 4 | ALA4229445 | organism-based format | Scientific Literature | |
6. | ALA4233807 | P | Stability of the compound in water | 6 | ALA4229445 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA4233808 | B | Inhibition of 5alpha-reductase2 (unknown origin) | Homo sapiens | 7 | ALA4229445 | single protein format | Scientific Literature |