| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4235834 | B | Inhibition of EGF-induced EGFR activation in human A431 cells pretreated for 60 mins followed by EGF addition and measured after 10 mins by ELISA | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 2. | ALA4235835 | B | Inhibition of VEGF-induced VEGFR2 activation in human U251 cells pretreated for 60 mins followed by VEGF addition and measured after 10 mins by ELISA | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 3. | ALA4235836 | B | Inhibition of PDGF-BB-induced PDGFRbeta activation in human SH-SY5Y cells pretreated for 60 mins followed by PDGF-BB addition and measured after 10 mins by ELISA | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 4. | ALA4235837 | F | Cytotoxicity against human A431 cells over-expressing EGFR | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 5. | ALA4235838 | F | Antiangiogenic activity in Leghorn chicken embryo chorioallantoic membrane after 40 hrs by microscopic analysis | Gallus gallus | 17 | tissue-based format | Scientific Literature | ||
| 6. | ALA4235841 | F | Potency index, ratio of sunitinib IC50 to test compound IC50 for antiangiogenic activity in Leghorn chicken embryo chorioallantoic membrane | Gallus gallus | 2 | tissue-based format | Scientific Literature | ||
| 7. | ALA4477909 | F | Cell cycle arrest in human HeLa cells assessed as accumulation at G2/M phase at 5 times IC50 after 18 hrs by flow cytometry (Rvb = 17.11 +/- 1.09%) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 8. | ALA4477910 | B | Induction of microtubule depolymerization in human A10 cells incubated for 18 hrs by indirect immunofluorescence analysis | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 9. | ALA4477911 | B | Induction of microtubule depolymerization in human A10 cells at 2 times EC50 incubated for 18 hrs by indirect immunofluorescence analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 10. | ALA4477912 | B | Induction of microtubule disruption in human HeLa cells assessed as multipolarization of spindle at 5 times IC50 incubated for 18 hrs by indirect immunofluorescence analysis relative to vehicle-treated control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 11. | ALA4477947 | F | Cytotoxicity against human MDA-MB-435 cells assessed as growth inhibition after 48 hrs by SRB assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 12. | ALA4477957 | F | Cytotoxicity against human SKOV3 cells assessed as growth inhibition after 48 hrs by SRB assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 13. | ALA4477975 | F | Antiproliferative activity against multidrug resistant human SKOV3 cells expressing MDR1-M6/6 after 48 hrs by SRB assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 14. | ALA4477976 | F | Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 15. | ALA4477977 | F | Antiproliferative activity against multidrug resistant human HeLa cells expressing wild type beta3 tubulin after 48 hrs by SRB assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 16. | ALA4477978 | F | Relative ratio of IC50 for human SKOV3 cells expressing MDR1-M6/6 to IC50 for human SKOV3 cells | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 17. | ALA4477979 | F | Relative ratio of IC50 for human HeLa cells expressing wild type beta3 tubulin to IC50 for human HeLa cells | Homo sapiens | 8 | cell-based format | Scientific Literature |
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