| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4236637 | B | Inhibition of N-terminal His-tagged BRD4 (BD1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide after 30 mins by alpha-screen assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 2. | ALA4236638 | B | Inhibition of N-terminal His-tagged BRD4 (BD2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide after 30 mins by alpha-screen assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 3. | ALA4236639 | B | Inhibition of N-terminal His-tagged BRD4 (BD1/BD2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide after 30 mins by alpha-screen assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 4. | ALA4236640 | B | Binding affinity to N-terminal His-tagged BRD4 (BD1) (unknown origin) assessed as change in melting temperature at 100 uM after 0.5 hrs by SYPRO orange protein staining-based thermal denaturation assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 5. | ALA4236641 | B | Binding affinity to N-terminal His-tagged BRD4 (BD1) (unknown origin) assessed as change in melting temperature at 100 uM after 4 hrs by SYPRO orange protein staining-based thermal denaturation assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 6. | ALA4236647 | F | Antiproliferative activity against human MV4-11 cells after 48 hrs by cell-titer 96 aqueous one solution reagent-based assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4236648 | F | Antiproliferative activity against human MV4-11 cells preincubated for 24 hrs by followed by compound washout measured after 48 hrs post compound washout by cell-titer 96 aqueous one solution reagent-based assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4236653 | B | Irreversible inhibition of BRD4 in human MV4-11 cells assessed as suppression of MYC mRNA levels preincubated for 4 hrs followed by compound washout measured after 4 to 24 hrs post washout by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4236654 | B | Irreversible inhibition of BRD4 in human MV4-11 cells assessed as suppression of BCL2 mRNA levels preincubated for 4 hrs followed by compound washout measured after 4 to 24 hrs post washout by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4236655 | B | Irreversible inhibition of BRD4 in human MV4-11 cells assessed as suppression of CCR1 mRNA levels preincubated for 4 hrs followed by compound washout measured after 4 to 24 hrs post washout by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4236656 | B | Irreversible inhibition of BRD4 in human MV4-11 cells assessed as suppression of GRP183 mRNA levels preincubated for 4 hrs followed by compound washout measured after 4 to 24 hrs post washout by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4236657 | B | Irreversible inhibition of BRD4 in human MV4-11 cells assessed as suppression of IL1RN mRNA levels preincubated for 4 hrs followed by compound washout measured after 4 to 24 hrs post washout by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4236664 | F | Antiproliferative activity against human MV4-11 cells incubated for 24 hrs followed by compound removal and further incubation for 48 hrs by cell-titer 96 aqueous one solution reagent-based assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4236671 | B | Binding affinity to PHIP (unknown origin) assessed as change in melting temperature at 100 uM after 0.5 to 4 hrs by SYPRO orange protein staining-based thermal denaturation assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 15. | ALA4236672 | B | Binding affinity to BRG1 (unknown origin) assessed as change in melting temperature at 100 uM after 0.5 to 4 hrs by SYPRO orange protein staining-based thermal denaturation assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 16. | ALA4236673 | B | Binding affinity to TAF1(2) (unknown origin) assessed as change in melting temperature at 100 uM after 0.5 to 4 hrs by SYPRO orange protein staining-based thermal denaturation assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 17. | ALA4236674 | B | Binding affinity to P300 (unknown origin) assessed as change in melting temperature at 100 uM after 0.5 to 4 hrs by SYPRO orange protein staining-based thermal denaturation assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 18. | ALA4236675 | B | Binding affinity to BRPF1 (unknown origin) assessed as change in melting temperature at 100 uM after 0.5 to 4 hrs by SYPRO orange protein staining-based thermal denaturation assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 19. | ALA4236676 | B | Binding affinity to CREBBP (unknown origin) assessed as change in melting temperature at 100 uM after 0.5 to 4 hrs by SYPRO orange protein staining-based thermal denaturation assay | Homo sapiens | 4 | single protein format | Scientific Literature |
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