# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4234610 | B | Inhibition of human recombinant His-tagged thymidylate synthase expressed in Escherichia coli at 100 uM after 1 hr by UV-vis spectrophotometric analysis relative to control | Homo sapiens | 9 | assay format | Scientific Literature | ||
2. | ALA4234611 | F | Cytotoxicity against human IGROV1 cells after 72 hrs | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
3. | ALA4234612 | F | Cytotoxicity against human 2008 cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
4. | ALA4234613 | F | Cytotoxicity against human C13 cells after 72 hrs | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
5. | ALA4234615 | B | Inhibition of thymidylate synthase in human IGROV1 cell lysate using [5-3H]dUMP as substrate assessed as decrease in residual activity at 5 uM after 60 mins by liquid scintillation counting analysis relative to control | Homo sapiens | 4 | assay format | Scientific Literature | ||
6. | ALA4234618 | F | Effect on TS protein expression in human IGROV1 cells by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
7. | ALA4234619 | F | Effect on DHFR protein expression in human IGROV1 cells by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
8. | ALA4234620 | F | Effect on HSP90 protein expression in human IGROV1 cells by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature |