| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4234610 | Binding | Inhibition of human recombinant His-tagged thymidylate synthase expressed in Escherichia coli at 100 uM after 1 hr by UV-vis spectrophotometric analysis relative to control | Homo sapiens | 9 | ALA4229466 | assay format | Scientific Literature | |
| 2. | ALA4234611 | Functional | Cytotoxicity against human IGROV1 cells after 72 hrs | Homo sapiens | 5 | ALA4229466 | cell-based format | Scientific Literature | |
| 3. | ALA4234612 | Functional | Cytotoxicity against human 2008 cells | Homo sapiens | 5 | ALA4229466 | cell-based format | Scientific Literature | |
| 4. | ALA4234613 | Functional | Cytotoxicity against human C13 cells after 72 hrs | Homo sapiens | 5 | ALA4229466 | cell-based format | Scientific Literature | |
| 5. | ALA4234615 | Binding | Inhibition of thymidylate synthase in human IGROV1 cell lysate using [5-3H]dUMP as substrate assessed as decrease in residual activity at 5 uM after 60 mins by liquid scintillation counting analysis relative to control | Homo sapiens | 4 | ALA4229466 | assay format | Scientific Literature | |
| 6. | ALA4234618 | Functional | Effect on TS protein expression in human IGROV1 cells by Western blot analysis | Homo sapiens | 3 | ALA4229466 | cell-based format | Scientific Literature | |
| 7. | ALA4234619 | Functional | Effect on DHFR protein expression in human IGROV1 cells by Western blot analysis | Homo sapiens | 3 | ALA4229466 | cell-based format | Scientific Literature | |
| 8. | ALA4234620 | Functional | Effect on HSP90 protein expression in human IGROV1 cells by Western blot analysis | Homo sapiens | 3 | ALA4229466 | cell-based format | Scientific Literature |
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