#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4234458	Functional	Inhibition of melanogenesis in HEMn assessed as reduction in intracellular melanin production at 1 uM after 72 hrs relative to control	Homo sapiens	1	ALA4229457	cell-based format	Scientific Literature
2.	ALA4234459	Binding	Inhibition of tyrosinase in mouse B16-F1 cell lysates assessed as reduction in melanin production at 25 uM using L-DOPA as substrate incubated for 30 mins followed by substrate addition measured after 30 mins	Mus musculus	7	ALA4229457	single protein format	Scientific Literature
3.	ALA4234460	ADME	Cytotoxicity against mouse B16-F1 cells assessed as reduction in cell viability at 25 uM after 72 hrs by MTT assay	Mus musculus	6	ALA4229457	cell-based format	Scientific Literature
4.	ALA4234461	Functional	Inhibition of alpha-MSH-stimulated melanogenesis in mouse B16-F1 cells assessed as reduction in intracellular melanin production at 25 uM after 72 hrs relative to control	Mus musculus	7	ALA4229457	cell-based format	Scientific Literature
5.	ALA4234462	Binding	Inhibition of adenylate cyclase in alpha-MSH-stimulated mouse B16-F1 cells assessed as reduction in cAMP-CREB signaling pathway-mediated TYR expression level at 25 uM after 48 to 72 hrs by Western blot analysis	Mus musculus	6	ALA4229457	cell-based format	Scientific Literature
6.	ALA4234463	Binding	Inhibition of adenylate cyclase in alpha-MSH-stimulated mouse B16-F1 cells assessed as reduction in cAMP-CREB signaling pathway-mediated DCT expression level at 25 uM after 48 to 72 hrs by Western blot analysis	Mus musculus	6	ALA4229457	cell-based format	Scientific Literature
7.	ALA4234464	Binding	Inhibition of adenylate cyclase in alpha-MSH-stimulated mouse B16-F1 cells assessed as reduction in cAMP-CREB signaling pathway-mediated TRP1 expression level at 25 uM after 48 to 72 hrs by Western blot analysis	Mus musculus	2	ALA4229457	cell-based format	Scientific Literature
8.	ALA4234465	Binding	Inhibition of adenylate cyclase in alpha-MSH-stimulated mouse B16-F1 cells assessed as reduction in cAMP-CREB signaling pathway-mediated MITF expression level at 25 uM after 48 to 72 hrs by Western blot analysis	Mus musculus	2	ALA4229457	cell-based format	Scientific Literature
9.	ALA4234466	Binding	Inhibition of adenylate cyclase in alpha-MSH-stimulated mouse B16-F1 cells assessed as reduction in CREB phosphorylation at 25 uM measured up to 360 mins by Western blot analysis	Mus musculus	1	ALA4229457	cell-based format	Scientific Literature
10.	ALA4234467	Binding	Inhibition of adenylate cyclase in mouse B16-F1 cell lysates assessed as reduction in forskolin-induced cAMP levels incubated for 6 hrs followed by forskolin stimulation measured after 30 mins by immuno assay	Mus musculus	1	ALA4229457	assay format	Scientific Literature
11.	ALA4234468	Binding	Inhibition of adenylate cyclase in mouse B16-F1 cell lysates assessed as reduction in alpha-MSH-induced cAMP levels incubated for 6 hrs followed by forskolin stimulation measured after 30 mins by immuno assay	Mus musculus	1	ALA4229457	assay format	Scientific Literature
12.	ALA4234469	Functional	Downregulation of adenylate cyclase protein expression level in alpha-MSH-stimulated mouse B16-F1 cells at 25 uM by Western blot analysis	Mus musculus	1	ALA4229457	cell-based format	Scientific Literature
13.	ALA4234470	Functional	Inhibition of melanogenesis in HEMn assessed as reduction in intracellular melanin production at 5 uM after 72 hrs relative to control	Homo sapiens	1	ALA4229457	cell-based format	Scientific Literature
14.	ALA4234471	Functional	Inhibition of melanogenesis in HEMn assessed as reduction in intracellular melanin production at 10 uM after 72 hrs relative to control	Homo sapiens	1	ALA4229457	cell-based format	Scientific Literature
15.	ALA4234472	Functional	Inhibition of melanogenesis in HEMn assessed as reduction in intracellular melanin production at 25 uM after 72 hrs relative to control	Homo sapiens	1	ALA4229457	cell-based format	Scientific Literature
16.	ALA4234473	Binding	Inhibition of tyrosinase in HEMn lysates assessed as reduction in melanin production using L-DOPA as substrate incubated for 30 mins followed by substrate addition measured after 30 mins	Homo sapiens	1	ALA4229457	single protein format	Scientific Literature