# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4236279 | A | Clearance in human hepatocytes assessed per million cells at 1 uM after 5 to 90 mins by LC-MS/MS analysis | Homo sapiens | 38 | ALA4229543 | cell-based format | Scientific Literature | |
2. | ALA4236280 | P | Solubility in PG/EtOH (96%) at 30 mg/mL after 24 hrs by UV-spectrometric method | 36 | ALA4229543 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA4236281 | P | Solubility in pH 7.4 phosphate buffer solution at 100 uM after 24 hrs by HPLC method | 38 | ALA4229543 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4236282 | B | Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence method | Homo sapiens | 38 | ALA4229543 | single protein format | Scientific Literature | |
5. | ALA4236283 | F | Pro-apoptotic activity in human HUT78 cells after 18 hrs by caspase-Glo 3/7 assay | Homo sapiens | 38 | ALA4229543 | cell-based format | Scientific Literature | |
6. | ALA4236284 | B | Inhibition of human recombinant HDAC1 using fluorogenic HDAC substrate after 15 mins by fluorimetrc method | Homo sapiens | 5 | ALA4229543 | single protein format | Scientific Literature | |
7. | ALA4236285 | B | Inhibition of human recombinant HDAC2 using fluorogenic HDAC substrate after 15 mins by fluorimetrc method | Homo sapiens | 5 | ALA4229543 | single protein format | Scientific Literature | |
8. | ALA4236286 | B | Inhibition of human recombinant HDAC3 using fluorogenic HDAC substrate after 10 mins by spectrophotometric method | Homo sapiens | 5 | ALA4229543 | single protein format | Scientific Literature | |
9. | ALA4236287 | B | Inhibition of human recombinant HDAC8 using fluorogenic HDAC substrate after 15 mins by fluorimetrc method | Homo sapiens | 5 | ALA4229543 | single protein format | Scientific Literature | |
10. | ALA4236288 | B | Inhibition of human recombinant HDAC4 using fluorogenic HDAC substrate class 2a after 30 mins by fluorimetrc method | Homo sapiens | 5 | ALA4229543 | single protein format | Scientific Literature | |
11. | ALA4236289 | B | Inhibition of human recombinant HDAC5 using fluorogenic HDAC substrate class 2a after 30 mins by fluorimetrc method | Homo sapiens | 5 | ALA4229543 | single protein format | Scientific Literature | |
12. | ALA4236290 | B | Inhibition of human recombinant HDAC7 using fluorogenic HDAC substrate class 2a after 45 mins by fluorimetrc method | Homo sapiens | 5 | ALA4229543 | single protein format | Scientific Literature | |
13. | ALA4236291 | B | Inhibition of human recombinant HDAC9 using fluorogenic HDAC substrate class 2a after 30 mins by fluorimetrc method | Homo sapiens | 5 | ALA4229543 | single protein format | Scientific Literature | |
14. | ALA4236292 | B | Inhibition of human recombinant HDAC6 using fluorogenic HDAC substrate after 30 mins by fluorimetrc method | Homo sapiens | 5 | ALA4229543 | single protein format | Scientific Literature | |
15. | ALA4236293 | B | Inhibition of human recombinant HDAC10 using fluorogenic HDAC substrate after 45 mins by fluorimetrc method | Homo sapiens | 5 | ALA4229543 | single protein format | Scientific Literature | |
16. | ALA4236294 | B | Inhibition of human recombinant SIRT1 using fluorogenic HDAC substrate after 20 mins by fluorimetrc method | Homo sapiens | 5 | ALA4229543 | single protein format | Scientific Literature | |
17. | ALA4236295 | B | Inhibition of human recombinant SIRT2 using fluoro-lysine sirtuin 2 deacetylase substrate after 60 mins by fluorimetrc method | Homo sapiens | 5 | ALA4229543 | single protein format | Scientific Literature | |
18. | ALA4236296 | B | Inhibition of human recombinant SIRT3 using fluoro-lysine sirtuin 2 deacetylase substrate after 45 mins by fluorimetrc method | Homo sapiens | 5 | ALA4229543 | single protein format | Scientific Literature | |
19. | ALA4236297 | B | Inhibition of SIRT7 (unknown origin) | Homo sapiens | 5 | ALA4229543 | single protein format | Scientific Literature | |
20. | ALA4236298 | B | Inhibition of human recombinant HDAC11 using fluorogenic HDAC substrate class 2a after 30 mins by fluorimetrc method | Homo sapiens | 5 | ALA4229543 | single protein format | Scientific Literature |