# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4235834 | B | Inhibition of EGF-induced EGFR activation in human A431 cells pretreated for 60 mins followed by EGF addition and measured after 10 mins by ELISA | Homo sapiens | 17 | ALA4229524 | cell-based format | Scientific Literature | |
2. | ALA4235835 | B | Inhibition of VEGF-induced VEGFR2 activation in human U251 cells pretreated for 60 mins followed by VEGF addition and measured after 10 mins by ELISA | Homo sapiens | 17 | ALA4229524 | cell-based format | Scientific Literature | |
3. | ALA4235836 | B | Inhibition of PDGF-BB-induced PDGFRbeta activation in human SH-SY5Y cells pretreated for 60 mins followed by PDGF-BB addition and measured after 10 mins by ELISA | Homo sapiens | 17 | ALA4229524 | cell-based format | Scientific Literature | |
4. | ALA4235837 | F | Cytotoxicity against human A431 cells over-expressing EGFR | Homo sapiens | 17 | ALA4229524 | cell-based format | Scientific Literature | |
5. | ALA4235838 | F | Antiangiogenic activity in Leghorn chicken embryo chorioallantoic membrane after 40 hrs by microscopic analysis | Gallus gallus | 17 | ALA4229524 | tissue-based format | Scientific Literature | |
6. | ALA4235842 | F | Induction of microtubule depolymerization in rat A10 cells after 18 hrs by indirect immunofluorescence method | Rattus norvegicus | 7 | ALA4229524 | cell-based format | Scientific Literature | |
7. | ALA4235843 | F | Antiproliferative activity against human MDA-MB-435 cells after 72 hrs by sulforhodamine B assay | Homo sapiens | 4 | ALA4229524 | cell-based format | Scientific Literature | |
8. | ALA4235844 | F | Antiproliferative activity against human SKOV3 cells after 72 hrs by sulforhodamine B assay | Homo sapiens | 4 | ALA4229524 | cell-based format | Scientific Literature | |
9. | ALA4235845 | F | Antiproliferative activity against human SKOV3-MDR1-M6/6 cells after 72 hrs by sulforhodamine B assay | Homo sapiens | 4 | ALA4229524 | assay format | Scientific Literature | |
10. | ALA4235846 | F | Resistance index, ratio of IC50 for human SKOV3-MDR1-M6/6 cells to IC50 for human SKOV3 cells | Homo sapiens | 4 | ALA4229524 | assay format | Scientific Literature | |
11. | ALA4235847 | F | Antiproliferative activity against human HeLa cells after 72 hrs by sulforhodamine B assay | Homo sapiens | 4 | ALA4229524 | cell-based format | Scientific Literature | |
12. | ALA4235848 | F | Antiproliferative activity against human wild-type Hela-beta3 cells after 72 hrs by sulforhodamine B assay | Homo sapiens | 4 | ALA4229524 | assay format | Scientific Literature | |
13. | ALA4235849 | F | Resistance index, ratio of IC50 for human HeLa cells to IC50 for human wild-type Hela-beta3 cells | Homo sapiens | 4 | ALA4229524 | assay format | Scientific Literature | |
14. | ALA4235850 | B | Inhibition of bovine brain tubulin assembly pretreated for 15 mins followed by GTP addition by spectrophotometric method | Bos taurus | 2 | ALA4229524 | assay format | Scientific Literature | |
15. | ALA4235851 | B | Inhibition of [3H]colchicine binding to bovine brain tubulin at 1 uM measured after 10 mins relative to control | Bos taurus | 2 | ALA4229524 | assay format | Scientific Literature | |
16. | ALA4235852 | B | Inhibition of [3H]colchicine binding to bovine brain tubulin at 5 uM measured after 10 mins relative to control | Bos taurus | 2 | ALA4229524 | assay format | Scientific Literature |