# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4235941 | Functional | Antitrypanosomal activity against Trypanosoma cruzi amastigote forms infected in African green monkey Vero cells | Trypanosoma cruzi | 30 | ALA4229528 | organism-based format | Scientific Literature | |
2. | ALA4235942 | ADME | Cytotoxicity against African green monkey Vero cells | Chlorocebus sabaeus | 30 | ALA4229528 | cell-based format | Scientific Literature | |
3. | ALA4235943 | Toxicity | Selectivity ratio of pEC50 for African green monkey Vero cells to pEC50 for Trypanosoma cruzi amastigote forms infected in African green monkey Vero cells | 30 | ALA4229528 | assay format | Scientific Literature | ||
4. | ALA4235944 | Physicochemical | Kinetic solubility of the compound in water up to 250 uM by laser nephelometry | 26 | ALA4229528 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4235945 | ADME | Intrinsic clearance in CD-1 mouse liver microsomes at 0.5 uM after 30 mins in presence of NADPH by UPLC-MS/MS analysis | Mus musculus | 30 | ALA4229528 | microsome format | Scientific Literature | |
6. | ALA4235946 | Binding | Inhibition of Trypanosoma cruzi CYP51 | Trypanosoma cruzi | 4 | ALA4229528 | single protein format | Scientific Literature |