| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4229719 | B | Inhibition of human factor D expressed in Escherichia coli using CVF-FB as substrate assessed as decrease in formation of factor B cleavage product Ba after 1 hr by ELISA | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 2. | ALA4394736 | B | Inhibition of 2-((1E,3E,5E)-5-(1-(6-((((3S,5S)-1-((1-carbamoyl-1H-indol-3-yl)carbamoyl)-5-((3-chloro-2-fluorobenzyl)carbamoyl)-3-fluoropyrrolidin-3-yl)methyl)amino)-6-oxohexyl)-3,3-dimethyl-5-sulfoindolin-2-ylidene)penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-5-sulfo-3H-indol-1-ium binding to biotin-labeled recombinant human FD expressed in Escherichia coli measured after 2 hrs by TR-FRET assay | Homo sapiens | 17 | assay format | Scientific Literature | ||
| 3. | ALA4394741 | B | Inhibition of FD-mediated alternative complementation pathway in 50% human whole blood assessed as reduction in zymosan-induced membrane-attack complex formation preincubated for 15 mins followed by zymosan stimulation and measured after 40 mins by ELISA | Homo sapiens | 17 | tissue-based format | Scientific Literature | ||
| 4. | ALA4394742 | A | Apparent permeability of the compound by PAMPA | 17 | assay format | Scientific Literature | |||
| 5. | ALA4394743 | B | Inhibition of F11a (unknown origin) | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 6. | ALA4394744 | B | Inhibition of tryptase-beta2 (unknown origin) | Homo sapiens | 10 | single protein format | Scientific Literature |
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