#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4233618	Binding	Poison activity at recombinant human topoisomerase-2alpha expressed in Saccharomyces cerevisiae assessed as stabilization of DNA-enzyme cleavage complex by measuring concentration required to generate 10% double-stranded DNA breaks using supercoiled pBR322 DNA as substrate incubated for 6 mins measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method	Homo sapiens	7	ALA4229437	assay format	Scientific Literature
2.	ALA4233619	Binding	Poison activity at recombinant human topoisomerase-2beta expressed in Saccharomyces cerevisiae assessed as stabilization of DNA-enzyme cleavage complex by measuring concentration required to generate 10% double-stranded DNA breaks using supercoiled pBR322 DNA as substrate incubated for 6 mins measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method	Homo sapiens	7	ALA4229437	assay format	Scientific Literature
3.	ALA4233620	Binding	Poison activity at recombinant human topoisomerase-2alpha expressed in Saccharomyces cerevisiae assessed as stabilization of DNA-enzyme cleavage complex at 25 uM using supercoiled pBR322 DNA as substrate incubated for 6 mins measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method	Homo sapiens	6	ALA4229437	assay format	Scientific Literature
4.	ALA4233621	Binding	Poison activity at recombinant human topoisomerase-2beta expressed in Saccharomyces cerevisiae assessed as stabilization of DNA-enzyme cleavage complex at 25 uM using supercoiled pBR322 DNA as substrate incubated for 6 mins measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method	Homo sapiens	6	ALA4229437	assay format	Scientific Literature
5.	ALA4233623	Binding	Poison activity at recombinant human topoisomerase-2alpha expressed in Saccharomyces cerevisiae assessed as inhibition of DNA religation using single-stranded DNA at 25 uM incubated for 6 mins by agarose gel electrophoresis method	Homo sapiens	6	ALA4229437	assay format	Scientific Literature
6.	ALA4233624	Binding	Poison activity at recombinant human topoisomerase-2beta expressed in Saccharomyces cerevisiae assessed as inhibition of DNA religation using single-stranded DNA at 25 uM incubated for 6 mins by agarose gel electrophoresis method	Homo sapiens	7	ALA4229437	assay format	Scientific Literature
7.	ALA4233625	Binding	Inhibition of recombinant human topoisomerase-2alpha expressed in Saccharomyces cerevisiae assessed as increase in double-stranded DNA cleavage at 25 uM using supercoiled pBR322 DNA as substrate incubated for 6 mins measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to etoposide	Homo sapiens	6	ALA4229437	assay format	Scientific Literature
8.	ALA4233627	Binding	Inhibition of recombinant human topoisomerase-2alpha expressed in Saccharomyces cerevisiae assessed as stabilization of DNA-enzyme cleavage complex at 25 uM incubated for 10 mins followed by incubation in drug-free buffer by agarose gel electrophoresis method	Homo sapiens	6	ALA4229437	assay format	Scientific Literature
9.	ALA4233629	Binding	Inhibition of recombinant human topoisomerase-2beta expressed in Saccharomyces cerevisiae assessed as stabilization of DNA-enzyme cleavage complex at 25 uM incubated for 6 mins followed by incubation in drug-free buffer by agarose gel electrophoresis method	Homo sapiens	6	ALA4229437	assay format	Scientific Literature
10.	ALA4233630	Binding	Inhibition of recombinant human topoisomerase-2alpha expressed in Saccharomyces cerevisiae assessed as increase in single-stranded DNA cleavage at 25 uM using supercoiled pBR322 DNA as substrate incubated for 6 mins measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to etoposide	Homo sapiens	6	ALA4229437	assay format	Scientific Literature
11.	ALA4233631	Binding	Inhibition of recombinant human topoisomerase-2alpha expressed in Saccharomyces cerevisiae assessed as increase in total DNA cleavage at 25 uM using supercoiled pBR322 DNA as substrate incubated for 6 mins measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to etoposide	Homo sapiens	6	ALA4229437	assay format	Scientific Literature
12.	ALA4233632	Binding	Inhibition of recombinant human topoisomerase-2beta expressed in Saccharomyces cerevisiae assessed as increase in double-stranded DNA cleavage at 25 uM using supercoiled pBR322 DNA as substrate incubated for 6 mins measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to etoposide	Homo sapiens	6	ALA4229437	assay format	Scientific Literature
13.	ALA4233633	Binding	Inhibition of recombinant human topoisomerase-2beta expressed in Saccharomyces cerevisiae assessed as increase in single-stranded DNA cleavage at 25 uM using supercoiled pBR322 DNA as substrate incubated for 6 mins measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to etoposide	Homo sapiens	6	ALA4229437	assay format	Scientific Literature
14.	ALA4233634	Binding	Inhibition of recombinant human topoisomerase-2beta expressed in Saccharomyces cerevisiae assessed as increase in total DNA cleavage at 25 uM using supercoiled pBR322 DNA as substrate incubated for 6 mins measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to etoposide	Homo sapiens	6	ALA4229437	assay format	Scientific Literature