| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4232710 | B | Inhibition of PI3Kdelta in Balb/c mouse splenocytes-derived B cells assessed as reduction in anti-IgM antibody-stimulated B cell proliferation after 2 days alamar blue assay | Mus musculus | 12 | cell-based format | Scientific Literature | ||
| 2. | ALA4232711 | B | Inhibition of recombinant human full length N-terminal His6-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf21 cells using PIP2 as substrate after 35 to 40 mins by HTRF assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 3. | ALA4232712 | B | Selectivity ratio of IC50 for recombinant human full length N-terminal His6-tagged PI3K p110alpha/p85alpha expressed in baculovirus infected Sf21 cells to IC50 for recombinant human full length N-terminal His6-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf21 cells | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 4. | ALA4232716 | A | Intrinsic clearance in CD-1 mouse liver microsomes at 0.2 uM up to 45 mins in presence of NADPH by LC-MS/MS analysis | Mus musculus | 6 | microsome format | Scientific Literature |
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