| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4231088 | B | Inhibition of recombinant N-terminal His6 tagged SUMO-fused Trypanosoma brucei brucei TC221 TAO MTS deletion mutant expressed in Escherichia coli FN102 preincubated for 2 mins followed by ubiquinol-1 addition measured over 2 mins by double beam-dual wavelength UV-spectrophotometry | Trypanosoma brucei brucei | 36 | assay format | Scientific Literature | ||
| 2. | ALA4231091 | F | Anti-parasitic activity against bloodstream trypomastigote stage of wild-type Trypanosoma brucei brucei Lister 427 after 48 hrs by resazurin-based assay | Trypanosoma brucei brucei | 30 | organism-based format | Scientific Literature | ||
| 3. | ALA4231092 | F | Anti-parasitic activity against bloodstream trypomastigote stage of wild-type Trypanosoma brucei brucei Lister 427 after 48 hrs in presence of 5 mM glycerol by resazurin-based assay | Trypanosoma brucei brucei | 30 | organism-based format | Scientific Literature | ||
| 4. | ALA4231093 | F | Anti-parasitic activity against bloodstream form of Trypanosoma congolense IL3000 after 48 hrs by resazurin-based assay | Trypanosoma congolense | 27 | organism-based format | Scientific Literature | ||
| 5. | ALA4231094 | F | Resistance factor, ratio of EC50 for bloodstream trypomastigote stage of wild-type Trypanosoma brucei brucei Lister 427 in presence of 5 mM glycerol to EC50 for bloodstream trypomastigote stage of wild-type Trypanosoma brucei brucei Lister 427 | Trypanosoma brucei brucei | 25 | organism-based format | Scientific Literature | ||
| 6. | ALA4231095 | A | Cytotoxicity against HFF cells assessed as reduction in cell viability after 30 hrs by resazurin-based assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 7. | ALA4231097 | F | Anti-parasitic activity against bloodstream trypomastigote stage of Trypanosoma brucei brucei with AQP2/3-dd knock out after 48 hrs by resazurin-based assay | Trypanosoma brucei brucei | 29 | organism-based format | Scientific Literature | ||
| 8. | ALA4231098 | F | Anti-parasitic activity against bloodstream trypomastigote stage of Trypanosoma brucei brucei with AQP triple knock out after 48 hrs by resazurin-based assay | Trypanosoma brucei brucei | 29 | organism-based format | Scientific Literature | ||
| 9. | ALA4231099 | F | Anti-parasitic activity against bloodstream trypomastigote stage of pentamidine/diminazene/melaminophenyl arsenical resistant Trypanosoma brucei B48 after 48 hrs by resazurin-based assay | Trypanosoma brucei | 29 | organism-based format | Scientific Literature | ||
| 10. | ALA4231100 | F | Resistance factor, ratio of EC50 for bloodstream trypomastigote stage of Trypanosoma brucei brucei with AQP2/3-dd knock out to EC50 for bloodstream trypomastigote stage of wild-type Trypanosoma brucei brucei Lister 427 | Trypanosoma brucei brucei | 25 | organism-based format | Scientific Literature | ||
| 11. | ALA4231101 | F | Resistance factor, ratio of EC50 for bloodstream trypomastigote stage of Trypanosoma brucei brucei AQP triple knock out to EC50 for bloodstream trypomastigote stage of wild-type Trypanosoma brucei brucei Lister 427 | Trypanosoma brucei brucei | 26 | organism-based format | Scientific Literature | ||
| 12. | ALA4231102 | F | Resistance factor, ratio of EC50 for bloodstream trypomastigote stage of pentamidine/diminazene/melaminophenyl arsenical resistant Trypanosoma brucei B48 to EC50 for bloodstream trypomastigote stage of wild-type Trypanosoma brucei brucei Lister 427 | 24 | assay format | Scientific Literature | |||
| 13. | ALA4231103 | T | Selectivity index, ratio of CC50 for HFF cells to EC50 for bloodstream trypomastigote stage of wild-type Trypanosoma brucei brucei Lister 427 | 15 | assay format | Scientific Literature |
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