# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4236704 | F | Growth inhibition of Trypanosoma cruzi Tulahuen amastigote forms infected in human THP1 cells at 100 uM after 72 hrs by beta-galactosidase reporter gene assay relative to control | Trypanosoma cruzi | 42 | ALA4229557 | organism-based format | Scientific Literature | |
2. | ALA4236706 | F | Growth inhibition of Trypanosoma cruzi Tulahuen amastigote forms infected in human THP1 cells after 72 hrs by beta-galactosidase reporter gene assay | Trypanosoma cruzi | 44 | ALA4229557 | organism-based format | Scientific Literature | |
3. | ALA4236707 | A | Cytotoxicity against human THP1 cells after 72 hrs by MTT assay | Homo sapiens | 43 | ALA4229557 | cell-based format | Scientific Literature | |
4. | ALA4236708 | T | Selectivity index, ratio of CC50 for human THP1 cells to GI50 for Trypanosoma cruzi Tulahuen amastigote forms infected in human THP1 cells | 9 | ALA4229557 | cell-based format | Scientific Literature | ||
5. | ALA4236709 | F | Growth inhibition of Leishmania amazonensis MHOM/BR/77/LTB0016 amastigote forms expressing beta-galactosidase infected in human THP1 cells at 100 uM by colorimetrc assay relative to control | Leishmania amazonensis | 42 | ALA4229557 | organism-based format | Scientific Literature | |
6. | ALA4236711 | B | Inhibition of Trypanosoma cruzi Trypanothione reductase expressed in Escherichia coli BL21(DE3) at 100 uM using T(S)2 as substrate incubated for 30 mins measured for 30 mins in presence of NADPH by DTNB reagent based assay relative to control | Trypanosoma cruzi | 8 | ALA4229557 | assay format | Scientific Literature |