# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4233168 | B | Inhibition of rabbit aortic ACAT1 | Oryctolagus cuniculus | 1 | assay format | Scientific Literature | ||
2. | ALA4233169 | A | Inhibition of rabbit intestinal ACAT2 | Oryctolagus cuniculus | 2 | assay format | Scientific Literature | ||
3. | ALA4233172 | B | Inhibition of SOAT1 in arterial homogenates isolated from 1% cholesterol fed New Zealand white rabbit assessed as reduction in cholesteryl oleate formation incubated for 5 mins in presence of [14C]-oleoyl-CoA and BSA complex by TLC method | Oryctolagus cuniculus | 67 | tissue-based format | Scientific Literature | ||
4. | ALA4233173 | A | Inhibition of SOAT2 in New Zealand white rabbit intestinal microsomes assessed as reduction in cholesteryl oleate formation incubated for 5 mins in presence of [14C]-oleoyl-CoA and BSA complex by TLC method | Oryctolagus cuniculus | 63 | assay format | Scientific Literature | ||
5. | ALA4233174 | B | Selectivity ratio of IC50 for inhibition of SOAT2 in New Zealand white rabbit intestinal microsomes to IC50 for inhibition of SOAT1 in arterial homogenates isolated from 1% cholesterol fed New Zealand white rabbit | Oryctolagus cuniculus | 63 | tissue-based format | Scientific Literature | ||
6. | ALA4233176 | B | Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholesterol | Mus musculus | 63 | cell-based format | Scientific Literature |