#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4234621	B	Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS peptide as substrate preincubated for 60 mins followed by substrate addition and measured after 60 mins in presence of PP2a by TR-FRET assay	Homo sapiens	6	ALA4229467	cell-based format	Scientific Literature
2.	ALA4234622	A	Half life in rat hepatocytes	Rattus norvegicus	1	ALA4229467	cell-based format	Scientific Literature
3.	ALA4234623	A	Protein binding in monkey plasma assessed as unbound fraction	Macaca mulatta	2	ALA4229467	cell-free format	Scientific Literature
4.	ALA4234624	A	Protein binding in human plasma assessed as unbound fraction	Homo sapiens	2	ALA4229467	cell-free format	Scientific Literature
5.	ALA4234625	A	Protein binding in rat plasma assessed as unbound fraction	Rattus norvegicus	2	ALA4229467	cell-free format	Scientific Literature
6.	ALA4234626	A	Intrinsic clearance in human primary hepatocytes assessed per million cells	Homo sapiens	2	ALA4229467	cell-based format	Scientific Literature
7.	ALA4234627	A	Half life in human primary hepatocytes at 10 uM	Homo sapiens	2	ALA4229467	cell-based format	Scientific Literature
8.	ALA4234628	B	Activation of recombinant AMPKbeta1 in cryopreserved human hepatocytes assessed as reduction in 14C-2-acetic acid incorporation after 1 hr by scintillation counting analysis	Homo sapiens	4	ALA4229467	cell-based format	Scientific Literature
9.	ALA4234629	B	Activation of AMPK in cryopreserved human hepatocytes assessed as increase in phosphorylation of acetyl-CoA carboxylase at Ser79 residue after 1 hr by Meso Scale Discovery assay	Homo sapiens	4	ALA4229467	cell-based format	Scientific Literature
10.	ALA4234630	B	Binding affinity to Bap-tagged human AMPKalpha1beta1gamma1 expressed in Escherichia coli BL21 cells by SPR analysis	Homo sapiens	6	ALA4229467	cell-based format	Scientific Literature
11.	ALA4234631	B	Binding affinity to Bap-tagged human AMPKalpha1beta1gamma1 expressed in Escherichia coli BL21 cells assessed as dissociation rate constant by SPR analysis	Homo sapiens	6	ALA4229467	cell-based format	Scientific Literature
12.	ALA4234632	B	Binding affinity to Bap-tagged human AMPKalpha1beta1gamma1 expressed in Escherichia coli BL21 cells assessed as association rate constant by SPR analysis	Homo sapiens	6	ALA4229467	cell-based format	Scientific Literature
13.	ALA4234633	B	Binding affinity to Bap-tagged human AMPKalpha1beta1gamma1 expressed in Escherichia coli BL21 cells assessed as dissociation half life by SPR analysis	Homo sapiens	6	ALA4229467	cell-based format	Scientific Literature
14.	ALA4234634	A	Apparent passive permeability of the compound in RRCK cells by FACS analysis	Canis lupus familiaris	6	ALA4229467	cell-based format	Scientific Literature
15.	ALA4234635	P	Lipophilicity, log D of the compound at pH 7.4 at 0.52 mg after 1 hr by shake-flask method		6	ALA4229467	small-molecule physicochemical format	Scientific Literature
16.	ALA4234636	B	Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells at 1 nM using Cy-5 SAMS peptide as substrate preincubated for 60 mins followed by substrate addition and measured after 60 mins in presence of PP2a by TR-FRET assay relative to AMP control	Homo sapiens	6	ALA4229467	cell-based format	Scientific Literature
17.	ALA4234637	B	Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma1 expressed in Escherichia coli BL21 cells at 1 nM using Cy-5 SAMS peptide as substrate preincubated for 60 mins followed by substrate addition and measured after 60 mins in presence of PP2a by TR-FRET assay relative to AMP control	Homo sapiens	6	ALA4229467	cell-based format	Scientific Literature
18.	ALA4234638	B	Activation of full-length recombinant N-terminal His-tagged human AMPKalpha1beta2gamma1 expressed in Escherichia coli BL21 cells at 0.5 nM using Cy-5 SAMS peptide as substrate preincubated for 60 mins followed by substrate addition and measured after 60 mins in presence of PP2a by TR-FRET assay relative to AMP control	Homo sapiens	6	ALA4229467	cell-based format	Scientific Literature
19.	ALA4234639	B	Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta1gamma1 expressed in Escherichia coli BL21 cells at 2 nM using Cy-5 SAMS peptide as substrate preincubated for 60 mins followed by substrate addition and measured after 60 mins in presence of PP2a by TR-FRET assay relative to AMP control	Homo sapiens	6	ALA4229467	cell-based format	Scientific Literature
20.	ALA4234640	B	Activation of full-length recombinant N-terminal His-tagged human AMPKalpha1beta1gamma1 expressed in Escherichia coli BL21 cells at 0.25 nM using Cy-5 SAMS peptide as substrate preincubated for 60 mins followed by substrate addition and measured after 60 mins in presence of PP2a by TR-FRET assay relative to AMP control	Homo sapiens	6	ALA4229467	cell-based format	Scientific Literature