# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4269350 | B | Inhibition of recombinant Aedes aegypti AChE1 expressed in sf9 insect cells using acetylthiocholine iodide as substrate measured over 60 secs by Ellman assay | Aedes aegypti | 19 | ALA4265992 | cell-based format | Scientific Literature | |
2. | ALA4269351 | B | Inhibition of recombinant Anopheles gambiae AChE1 expressed in sf9 insect cells using acetylthiocholine iodide as substrate measured over 60 secs by Ellman assay | Anopheles gambiae | 19 | ALA4265992 | cell-based format | Scientific Literature | |
3. | ALA4269352 | B | Inhibition of recombinant Anopheles gambiae AChE1 G122S mutant expressed in sf9 insect cells using acetylthiocholine iodide as substrate measured over 60 secs by Ellman assay | Anopheles gambiae | 19 | ALA4265992 | cell-based format | Scientific Literature | |
4. | ALA4269353 | A | Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate measured over 60 secs by Ellman assay | Homo sapiens | 19 | ALA4265992 | single protein format | Scientific Literature | |
5. | ALA4269354 | F | Insecticidal activity against five day old female adult Aedes aegypti Mombasa assessed as mortality at 4.26 ug administered topically measured after 24 hrs relative to control | Aedes aegypti | 3 | ALA4265992 | organism-based format | Scientific Literature | |
6. | ALA4269355 | F | Insecticidal activity against five day old female adult Anopheles gambiae Kisumu assessed as mortality at 4.26 ug administered topically measured after 24 hrs relative to control | Anopheles gambiae | 1 | ALA4265992 | organism-based format | Scientific Literature | |
7. | ALA4269356 | F | Insecticidal activity against topically dosed five day old female adult Aedes aegypti Mombasa assessed as mortality measured after 24 hrs | Aedes aegypti | 1 | ALA4265992 | organism-based format | Scientific Literature | |
8. | ALA4269359 | F | Insecticidal activity against five day old female adult Aedes aegypti Mombasa assessed as mortality rate at 57.3 ng administered via micro-injection measured after 24 hrs relative to control | Aedes aegypti | 1 | ALA4265992 | organism-based format | Scientific Literature | |
9. | ALA4269363 | F | Insecticidal activity against five day old female adult Aedes aegypti Mombasa assessed as mortality rate at 57.3 ng administered via micro-injection measured after 48 hrs relative to control | Aedes aegypti | 1 | ALA4265992 | organism-based format | Scientific Literature | |
10. | ALA4269370 | B | Selectivity ratio of IC50 for recombinant human AChE to IC50 for recombinant Aedes aegypti AChE1 | 17 | ALA4265992 | assay format | Scientific Literature | ||
11. | ALA4269371 | B | Selectivity ratio of IC50 for recombinant human AChE to IC50 for recombinant Anopheles gambiae AChE1 | 17 | ALA4265992 | assay format | Scientific Literature |