# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4251999 | Binding | Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured for 4 mins by FLIPR assay | Homo sapiens | 170 | ALA4251550 | cell-based format | Scientific Literature | |
2. | ALA4252000 | ADME | Apparent permeability in MDCK cells | Canis lupus familiaris | 6 | ALA4251550 | cell-based format | Scientific Literature | |
3. | ALA4252001 | ADME | Efflux ratio of apparent permeability in MDCK cells expressing Pgp | Canis lupus familiaris | 6 | ALA4251550 | cell-based format | Scientific Literature | |
4. | ALA4252002 | ADME | Efflux ratio of apparent permeability in MDCK cells expressing BCRP | Canis lupus familiaris | 6 | ALA4251550 | cell-based format | Scientific Literature | |
5. | ALA4252003 | Physicochemical | Solubility of compound in FaSSIF | 6 | ALA4251550 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4252004 | ADME | Intrinsic clearance in mouse liver microsomes | Mus musculus | 21 | ALA4251550 | microsome format | Scientific Literature | |
7. | ALA4252021 | Binding | Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured for 4 mins in presence of GlyRs inhibitor strychnine by FLIPR assay | Homo sapiens | 2 | ALA4251550 | cell-based format | Scientific Literature |