| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4271818 | F | Antiproliferative activity against human A549 cells after 48 hrs by CCK8 assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 2. | ALA4271819 | F | Antiproliferative activity against human AGS cells after 48 hrs by CCK8 assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 3. | ALA4271820 | F | Antiproliferative activity against human K562 cells after 48 hrs by CCK8 assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 4. | ALA4271821 | F | Antiproliferative activity against human HCT116 cells after 48 hrs by CCK8 assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 5. | ALA4271822 | F | Antiproliferative activity against human BxPC3 cells after 48 hrs by CCK8 assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 6. | ALA4271823 | F | Antiproliferative activity against human SKOV3 cells after 48 hrs by CCK8 assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 7. | ALA4271824 | A | Hemolytic activity against rabbit erythrocytes assessed as hemolysis at 100 uM measured after 1 hr | Oryctolagus cuniculus | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA4271825 | P | 1-Octanol/water partition coefficient, log P of the compound after 24 hrs by shake-flask method | 8 | small-molecule physicochemical format | Scientific Literature | |||
| 9. | ALA4271826 | A | Antiproliferative activity against HEK293T cells after 48 hrs by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4271827 | A | Antiproliferative activity against HUVEC after 48 hrs by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4271828 | A | Antiproliferative activity against human LO2 cells after 48 hrs by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA4271829 | T | Selectivity index, ratio of IC50 for HEK293T cells to IC50 for human AGS cells | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA4271830 | T | Selectivity index, ratio of IC50 for HUVEC to IC50 for human AGS cells | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA4271831 | T | Selectivity index, ratio of IC50 for human LO2 cells to IC50 for human AGS cells | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA4271832 | B | Inhibition of recombinant human NAE assessed as reduction in Ubc12-NEDD8 conjugation level pretreated for 10 mins followed by Mg2+ and ATP addition measured after 60 mins by Western blot analysis | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 16. | ALA4271833 | B | Inhibition of NAE in human AGS cells assessed as reduction in Uba3-NEDD8 conjugation level after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4271834 | B | Inhibition of NAE in human AGS cells assessed as reduction in Ubc12-NEDD8 conjugation level after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4271835 | B | Inhibition of NAE in human AGS cells assessed as reduction in Cullins-NEDD8 conjugation level after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4271836 | B | Inhibition of NAE-mediated CRL neddylation in human AGS cells assessed as increase in CDT1 level up to 10 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4271837 | B | Inhibition of NAE-mediated CRL neddylation in human AGS cells assessed as increase in p27 level up to 10 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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