#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4266930	Binding	Agonist activity at human TLR7 expressed in HEK293 cells after 6 hrs by NFkappaB-luciferase reporter gene assay	Homo sapiens	52	ALA4265889	cell-based format	Scientific Literature
2.	ALA4266931	Binding	Agonist activity at human TLR8 expressed in HEK293 cells after 6 hrs by NFkappaB-luciferase reporter gene assay	Homo sapiens	52	ALA4265889	cell-based format	Scientific Literature
3.	ALA4266932	ADME	Cytotoxicity against HEK293 cells transfected with the CMV-TLR7 construct assessed as reduction in cell viability after 6 hrs by ATPlite assay	Homo sapiens	51	ALA4265889	cell-based format	Scientific Literature
4.	ALA4266934	Binding	Agonist activity at TLR7 in human PBMC assessed as suppression of HCV replicon replication in human HuH7 luc/neo cells harboring RNA encoding bicistronic expression construct comprising wild type HCV type 1b NS3-NS5B regions exposed to conditioned media from compound treated PBMCs after 24 hrs by luciferase reporter gene assay	Homo sapiens	37	ALA4265889	cell-based format	Scientific Literature
5.	ALA4266935	Binding	Displacement of 3H-dofetilide from human ERG	Homo sapiens	6	ALA4265889	single protein format	Scientific Literature
6.	ALA4266936	ADME	Drug metabolism in mouse liver microsomes at 1 uM after 15 mins	Mus musculus	6	ALA4265889	microsome format	Scientific Literature
7.	ALA4266937	ADME	Drug metabolism in human liver microsomes at 1 uM after 15 mins	Homo sapiens	4	ALA4265889	microsome format	Scientific Literature
8.	ALA4266938	ADME	Tmax in C57BL/6 mouse plasma at 5 mg/kg, po	Mus musculus	1	ALA4265889	organism-based format	Scientific Literature
9.	ALA4266939	ADME	Cmax in C57BL/6 mouse plasma at 5 mg/kg, po	Mus musculus	1	ALA4265889	organism-based format	Scientific Literature
10.	ALA4266940	ADME	Cmax in C57BL/6 mouse liver at 5 mg/kg, po	Mus musculus	1	ALA4265889	organism-based format	Scientific Literature
11.	ALA4266941	ADME	AUC (0 to last) in C57BL/6 mouse plasma at 5 mg/kg, po	Mus musculus	1	ALA4265889	organism-based format	Scientific Literature
12.	ALA4266942	ADME	AUC (0 to last) in C57BL/6 mouse liver at 5 mg/kg, po	Mus musculus	1	ALA4265889	organism-based format	Scientific Literature
13.	ALA4266943	ADME	Protein binding in mouse plasma	Mus musculus	1	ALA4265889	cell-free format	Scientific Literature
14.	ALA4266944	ADME	Inhibition of CYP3A4 (unknown origin)	Homo sapiens	1	ALA4265889	single protein format	Scientific Literature
15.	ALA4266945	ADME	Inhibition of CYP2C8 (unknown origin)	Homo sapiens	1	ALA4265889	single protein format	Scientific Literature
16.	ALA4266946	ADME	Inhibition of CYP2C9 (unknown origin)	Homo sapiens	1	ALA4265889	single protein format	Scientific Literature
17.	ALA4266947	ADME	Inhibition of CYP2D6 (unknown origin)	Homo sapiens	1	ALA4265889	single protein format	Scientific Literature
18.	ALA4266948	ADME	Inhibition of CYP1A2 (unknown origin)	Homo sapiens	1	ALA4265889	single protein format	Scientific Literature
19.	ALA4266949	ADME	Inhibition of CYP2C19 (unknown origin)	Homo sapiens	1	ALA4265889	single protein format	Scientific Literature
20.	ALA4266950	Functional	Induction of innate immune response in C57BL/6 mouse assessed as IFNalpha Cmax in plasma at 5 mg/kg, po	Mus musculus	1	ALA4265889	organism-based format	Scientific Literature