# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4269302 | B | Inhibition of recombinant Cryptococcus neoformans His-tagged IMPDH expressed in Escherichia coli BL21 (DE3) using IMP as substrate in presence of NAD | Cryptococcus neoformans | 16 | ALA4265991 | assay format | Scientific Literature | |
2. | ALA4269303 | B | Inhibition of recombinant human His-tagged IMPDH1 expressed in Escherichia coli BL21 (DE3) using IMP as substrate in presence of NAD | Homo sapiens | 16 | ALA4265991 | assay format | Scientific Literature | |
3. | ALA4269304 | B | Inhibition of recombinant human His-tagged IMPDH2 expressed in Escherichia coli BL21 (DE3) using IMP as substrate in presence of NAD | Homo sapiens | 16 | ALA4265991 | assay format | Scientific Literature | |
4. | ALA4269305 | B | Selectivity index, ratio of IC50 for recombinant human His-tagged IMPDH1 to IC50 for recombinant Cryptococcus neoformans His-tagged IMPDH | 2 | ALA4265991 | assay format | Scientific Literature | ||
5. | ALA4269306 | B | Selectivity index, ratio of IC50 for recombinant human His-tagged IMPDH2 to IC50 for recombinant Cryptococcus neoformans His-tagged IMPDH | 2 | ALA4265991 | assay format | Scientific Literature | ||
6. | ALA4269307 | F | Antifungal activity against Candida albicans after 24 hrs by two fold serial dilution method | Candida albicans | 17 | ALA4265991 | organism-based format | Scientific Literature | |
7. | ALA4269308 | F | Antifungal activity against Cryptococcus neoformans after 24 hrs by resazurin-dye based two fold serial dilution method | Cryptococcus neoformans | 17 | ALA4265991 | organism-based format | Scientific Literature | |
8. | ALA4269309 | A | Cytotoxicity against HEK293 cells after 24 hrs by resazurin dye-based fluorescence analysis | Homo sapiens | 16 | ALA4265991 | cell-based format | Scientific Literature | |
9. | ALA4269310 | A | Cytotoxicity against human HepG2 cells after 24 hrs by resazurin dye-based fluorescence analysis | Homo sapiens | 16 | ALA4265991 | cell-based format | Scientific Literature |