#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4256746	F	Cognition enhancement activity in double APP/PS1 transgenic Alzheimer's disease C57BL/6 mouse model assessed as decrease in latency to find goal platform at 100 mg/kg, ip administered as single daily dose at 5 times per week for first 1 week followed by oral administration as single daily dose at 5 times per week for next 7 weeks by Morris water maze test relative to control	Mus musculus	1		organism-based format	Scientific Literature
2.	ALA4256747	F	Cognition enhancement activity in double APP/PS1 transgenic Alzheimer's disease C57BL/6 mouse model assessed as discrimination index at 100 mg/kg, ip administered as single daily dose at 5 times per week for first 1 week followed by oral administration as single daily dose at 5 times per week for next 7 weeks by novel object recognition test relative to control	Mus musculus	1		organism-based format	Scientific Literature
3.	ALA4256748	F	Cognition enhancement activity in double APP/PS1 transgenic Alzheimer's disease C57BL/6 mouse model assessed as increase in time spent in goal quadran at 100 mg/kg, ip administered as single daily dose at 5 times per week for first 1 week followed by oral administration as single daily dose at 5 times per week for next 7 weeks by Morris water maze test relative to control	Mus musculus	1		organism-based format	Scientific Literature
4.	ALA4256749	A	Effect on cognition activity in wild type C57BL/6 mouse assessed as decrease in time spent in goal quadran at 100 mg/kg, ip administered as single daily dose at 5 times per week for first 1 week followed by oral administration as single daily dose at 5 times per week for next 7 weeks by Morris water maze test relative to control	Mus musculus	1		organism-based format	Scientific Literature
5.	ALA4256750	F	Cardioprotective activity in 30 mins coronary artery ligated I/R AMI ICR mouse model assessed as reduction in infract size at 30 mg/kg, po measured at 24 hrs post surgery by TTC-staining based assay	Mus musculus	1		organism-based format	Scientific Literature
6.	ALA4256751	F	Cardioprotective activity in 30 mins coronary artery ligated I/R AMI ICR mouse model assessed as reduction in troponin-1 levels at 30 mg/kg, po measured at 24 hrs post surgery by ELISA	Mus musculus	1		organism-based format	Scientific Literature
7.	ALA4256752	B	Inhibition of NLRP3 in mouse J774A.1 cells assessed as reduction in LPS-stimulated IL-1beta levels pre-incubated with LPS for 4.5 hrs followed by incubation for 30 mins in presence of ATP and measured after 30 mins by ELISA	Mus musculus	29		cell-based format	Scientific Literature
8.	ALA4256755	B	Inhibition of AIM2 in mouse J774A.1 cells assessed as reduction in LPS-stimulated IL-1beta levels at 10 uM incubated for 1 hr with LPS followed by flagellin stimulation for 6 hrs by ELISA	Mus musculus	4		cell-based format	Scientific Literature
9.	ALA4256756	B	Inhibition of NLRC4 in mouse J774A.1 cells assessed as reduction in LPS-stimulated IL-1beta levels at 10 uM incubated for 1 hr with LPS followed by (poly(dA:dT)) stimulation for 8 hrs by ELISA	Mus musculus	4		cell-based format	Scientific Literature
10.	ALA4256758	F	Cardioprotective activity in 75 mins coronary artery ligated I/R AMI ICR mouse model assessed as reduction in infract size at 30 mg/kg, po measured at 24 hrs post surgery by TTC-staining based assay	Mus musculus	1		organism-based format	Scientific Literature
11.	ALA5119777	F	Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as cleavage of pro-caspase 1 to p20 measured at 5 to 20 microM after 2.5 hrs by Western blot analysis	Mus musculus	2		cell-based format	Scientific Literature
12.	ALA5119798	F	Inhibition of NLRP3 inflammasome activation in mouse J774.A1 cells assessed as cleavage of pro-caspase 1 to p20 measured at 20 microM after 2.5 hrs by Western blot analysis	Mus musculus	1		cell-based format	Scientific Literature