| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4268661 | Functional | Potency index, ratio of 5-fluorouracil IC50 to test compound IC50 for human A549 cells | Homo sapiens | 1 | ALA4265955 | cell-based format | Scientific Literature | |
| 2. | ALA4268662 | Functional | Potency index, ratio of 5-fluorouracil IC50 to test compound IC50 for human MCF7 cells | Homo sapiens | 1 | ALA4265955 | cell-based format | Scientific Literature | |
| 3. | ALA4268663 | Functional | Potency index, ratio of 5-fluorouracil IC50 to test compound IC50 for human T84 cells | Homo sapiens | 1 | ALA4265955 | cell-based format | Scientific Literature | |
| 4. | ALA4268664 | Functional | Antiproliferative activity against human MCF7 cells after 3 days by sulforhodamine B assay | Homo sapiens | 9 | ALA4265955 | cell-based format | Scientific Literature | |
| 5. | ALA4268665 | Functional | Antiproliferative activity against human T84 cells after 3 days by sulforhodamine B assay | Homo sapiens | 9 | ALA4265955 | cell-based format | Scientific Literature | |
| 6. | ALA4268666 | Functional | Antiproliferative activity against human A549 cells after 3 days by sulforhodamine B assay | Homo sapiens | 9 | ALA4265955 | cell-based format | Scientific Literature | |
| 7. | ALA4268668 | ADME | Cytotoxicity against human PBMC assessed as reduction in cell viability at 10 uM by MTT assay relative to control | Homo sapiens | 2 | ALA4265955 | cell-based format | Scientific Literature | |
| 8. | ALA4268669 | ADME | Cytotoxicity against human PBMC assessed as cell viability at 1 uM by MTT assay relative to control | Homo sapiens | 2 | ALA4265955 | cell-based format | Scientific Literature | |
| 9. | ALA4268670 | ADME | Cytotoxicity against human PBMC assessed as cell viability at 2.5 uM by MTT assay relative to control | Homo sapiens | 2 | ALA4265955 | cell-based format | Scientific Literature | |
| 10. | ALA4268671 | ADME | Cytotoxicity against human PBMC assessed as cell viability at 5 uM by MTT assay relative to control | Homo sapiens | 2 | ALA4265955 | cell-based format | Scientific Literature | |
| 11. | ALA4268673 | Functional | Cell cycle arrest in human A549 cells assessed as accumulation at G2/M phase at IC50 after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 8.8%) | Homo sapiens | 1 | ALA4265955 | cell-based format | Scientific Literature | |
| 12. | ALA4268674 | Functional | Cell cycle arrest in human A549 cells assessed as accumulation at G0/G1 phase at IC50 after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 60.6%) | Homo sapiens | 1 | ALA4265955 | cell-based format | Scientific Literature | |
| 13. | ALA4268675 | Functional | Cell cycle arrest in human A549 cells assessed as accumulation at sub-G1 phase at IC50 after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 2.6%) | Homo sapiens | 1 | ALA4265955 | cell-based format | Scientific Literature | |
| 14. | ALA4268676 | Functional | Cell cycle arrest in human A549 cells assessed as reduction in accumulation at G1 phase at IC50 after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4265955 | cell-based format | Scientific Literature | |
| 15. | ALA4268677 | Functional | Cell cycle arrest in human A549 cells assessed as reduction in accumulation at S phase at IC50 after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4265955 | cell-based format | Scientific Literature | |
| 16. | ALA4268678 | Functional | Cell cycle arrest in human A549 cells assessed as reduction in accumulation at G2/M phase at IC50 after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4265955 | cell-based format | Scientific Literature | |
| 17. | ALA4268679 | Functional | Induction of apoptosis in human A549 cells assessed as viable cells at IC50 after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry (Rvb = 83.6%) | Homo sapiens | 1 | ALA4265955 | cell-based format | Scientific Literature | |
| 18. | ALA4268680 | Functional | Induction of apoptosis in human A549 cells assessed as total apoptotic cells at IC50 after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry (Rvb = 13.2%) | Homo sapiens | 1 | ALA4265955 | cell-based format | Scientific Literature | |
| 19. | ALA4268681 | Functional | Induction of apoptosis in human A549 cells assessed as increase in Bax to Bcl2 ratio at 0.5 to 1 times IC50 after 24 hrs Western blot analysis | Homo sapiens | 1 | ALA4265955 | cell-based format | Scientific Literature |
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