# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4276233 | Binding | Inhibition of recombinant His10-tagged ZZ-HCV3C-BRM ATPase-SnAC (636 to 1331 residues) (unknown origin) expressed in insect sf9 cells preincubated for 5 mins followed by pCMV-dR8.91 plasmid and ATP addition measured after 60 mins by ADP-Glo assay | Homo sapiens | 14 | ALA4270662 | cell-based format | Scientific Literature | |
2. | ALA4276234 | Binding | Inhibition of recombinant His6-tagged BRG1 ATPase-SnAC (658 to 1361 residues) (unknown origin) expressed in insect sf9 cells preincubated for 5 mins followed by pCMV-dR8.91 plasmid and ATP addition measured after 60 mins by ADP-Glo assay | Homo sapiens | 14 | ALA4270662 | cell-based format | Scientific Literature | |
3. | ALA4276242 | Binding | Inhibition of BRM/BRG1 mutant in human NCI-H1299 cells assessed as reduction in KRT80 gene expression after 24 hrs by luciferase reporter gene assay | Homo sapiens | 7 | ALA4270662 | cell-based format | Scientific Literature | |
4. | ALA4276243 | Binding | Inhibition of BRM/BRG1 mutant-dependant cell proliferation in human SKMEL5 cells after 6 days by celltiter-glo luminescent cell viability assay | Homo sapiens | 7 | ALA4270662 | cell-based format | Scientific Literature | |
5. | ALA4276244 | Functional | Antiproliferative activity against human SBC5 cells assessed as cell growth inhibition after 6 days by celltiter-glo luminescent cell viability assay | Homo sapiens | 7 | ALA4270662 | cell-based format | Scientific Literature | |
6. | ALA4276257 | Binding | Binding affinity to N-terminal MBP-fused human BRM RecA domain (705 to 960 residues) expressed in Escherichia coli BL21 Star (DE3) by ITC method | Homo sapiens | 1 | ALA4270662 | assay format | Scientific Literature | |
7. | ALA4276258 | Binding | Binding affinity to N-terminal MBP-fused human BRM RecA domain E852Q mutant expressed in Escherichia coli BL21 Star (DE3) by ITC method | Homo sapiens | 1 | ALA4270662 | assay format | Scientific Literature |