# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4257019 | B | Binding affinity to N-terminal GST tagged CNK PH domain (unknown origin) by SPR spectroscopy | Homo sapiens | 21 | ALA4257006 | assay format | Patent Bioactivity Data | |
2. | ALA4257022 | B | Competitive inhibition of CNK1 (unknown origin) binding to PIP3 (unknown origin) at 50 uM by SPR spectroscopy | Homo sapiens | 19 | ALA4257006 | assay format | Patent Bioactivity Data | |
3. | ALA4257023 | A | Growth inhibition of human NCI-H661 cells expressing wild type KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 16 | ALA4257006 | cell-based format | Patent Bioactivity Data | |
4. | ALA4257024 | A | Growth inhibition of human NCI-H226 cells expressing wild type KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 16 | ALA4257006 | cell-based format | Patent Bioactivity Data | |
5. | ALA4257025 | A | Growth inhibition of human NCI-H1975 cells expressing wild type KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 16 | ALA4257006 | cell-based format | Patent Bioactivity Data | |
6. | ALA4257026 | A | Growth inhibition of human HCC95 cells expressing wild type KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 16 | ALA4257006 | cell-based format | Patent Bioactivity Data | |
7. | ALA4257027 | F | Growth inhibition of human NCI-H1993 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | ALA4257006 | cell-based format | Patent Bioactivity Data | |
8. | ALA4257028 | F | Growth inhibition of human A549 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | ALA4257006 | cell-based format | Patent Bioactivity Data | |
9. | ALA4257029 | F | Growth inhibition of human NCI-H157 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | ALA4257006 | cell-based format | Patent Bioactivity Data | |
10. | ALA4257030 | F | Growth inhibition of human HCC515 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | ALA4257006 | cell-based format | Patent Bioactivity Data | |
11. | ALA4257031 | F | Growth inhibition of human NCI-H1944 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | ALA4257006 | cell-based format | Patent Bioactivity Data | |
12. | ALA4257032 | F | Growth inhibition of human NCI-H1373 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | ALA4257006 | cell-based format | Patent Bioactivity Data | |
13. | ALA4257033 | F | Growth inhibition of human HCC44 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | ALA4257006 | cell-based format | Patent Bioactivity Data | |
14. | ALA4257034 | F | Growth inhibition of human NCI-H1792 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | ALA4257006 | cell-based format | Patent Bioactivity Data | |
15. | ALA4257035 | F | Growth inhibition of human NCI-H23 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | ALA4257006 | cell-based format | Patent Bioactivity Data | |
16. | ALA4257036 | F | Growth inhibition of human NCI-H2122 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | ALA4257006 | cell-based format | Patent Bioactivity Data | |
17. | ALA4257037 | F | Antiproliferative activity against human NSCLC cells expressing mutant KRAS assessed as inhibition of 2D cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 15 | ALA4257006 | cell-based format | Patent Bioactivity Data | |
18. | ALA4257038 | F | Antiproliferative activity against human NSCLC cells expressing mutant KRAS assessed as inhibition of 3D cell growth after 3 days | Homo sapiens | 6 | ALA4257006 | cell-based format | Patent Bioactivity Data | |
19. | ALA4420443 | B | Binding affinity to N-terminal GST-tagged CNK PHD (unknown origin) by SPR assay | Homo sapiens | 22 | ALA4420064 | single protein format | Patent Bioactivity Data | |
20. | ALA4420446 | B | Competitive binding affinity to N-terminal GST-tagged CNK PHD (unknown origin) assessed as inhibition of CNK1 binding to PIP3 at 50 uM by SPR assay relative to control | Homo sapiens | 14 | ALA4420064 | single protein format | Patent Bioactivity Data |