# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4263515 | B | Inhibition of human DHODH at 100 uM | Homo sapiens | 11 | single protein format | Scientific Literature | ||
2. | ALA4263517 | B | Inhibition of recombinant oligo-histidine-tagged Leishmania major DHODH expressed in Escherichia coli BL21(DE3) cells at 100 uM using DHO as substrate measured after 60 secs | Leishmania major | 10 | cell-based format | Scientific Literature | ||
3. | ALA4263518 | B | Inhibition of recombinant oligo-histidine-tagged Leishmania major DHODH expressed in Escherichia coli BL21(DE3) cells using DHO as substrate measured after 60 secs | Leishmania major | 56 | cell-based format | Scientific Literature | ||
4. | ALA4263519 | B | Binding affinity to Leishmania major DHODH assessed as change in melting temperature at 100 uM by differential scanning fluorimetry-based ThermoFMN assay | Leishmania major | 12 | single protein format | Scientific Literature | ||
5. | ALA4263520 | B | Binding affinity to Leishmania major DHODH assessed as change in melting temperature at 500 uM by differential scanning fluorimetry-based ThermoFMN assay | Leishmania major | 12 | single protein format | Scientific Literature | ||
6. | ALA4263521 | B | Binding affinity to Leishmania major DHODH assessed as change in melting temperature at 1000 uM by differential scanning fluorimetry-based ThermoFMN assay | Leishmania major | 12 | single protein format | Scientific Literature | ||
7. | ALA4263522 | B | Binding affinity to Leishmania major DHODH assessed as change in melting temperature at 100 uM by SYPRO orange dye-based differential scanning fluorimetry | Leishmania major | 12 | single protein format | Scientific Literature | ||
8. | ALA4263523 | B | Binding affinity to Leishmania major DHODH assessed as change in melting temperature at 500 uM by SYPRO orange dye-based differential scanning fluorimetry | Leishmania major | 12 | single protein format | Scientific Literature | ||
9. | ALA4263524 | B | Binding affinity to Leishmania major DHODH assessed as change in melting temperature at 1000 uM by SYPRO orange dye-based differential scanning fluorimetry | Leishmania major | 12 | single protein format | Scientific Literature | ||
10. | ALA4263527 | F | Antileishmanial activity against Leishmania amazonensis promastigotes | Leishmania amazonensis | 2 | organism-based format | Scientific Literature | ||
11. | ALA4263528 | F | Antileishmanial activity against Leishmania braziliensis promastigotes | Leishmania braziliensis | 1 | organism-based format | Scientific Literature |