| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4269071 | B | Inhibition of MARK4 (unknown origin) (59 to 368 residues) expressed in Escherichia coli M15 in presence of [gamma-32P]ATP by ATPase assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 2. | ALA4269072 | B | Inhibition of MARK4 (unknown origin) (59 to 368 residues) expressed in Escherichia coli M15 3 to 10 uM by dot blot assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 3. | ALA4269073 | B | Binding affinity to MARK4 (unknown origin) (59 to 368 residues) expressed in Escherichia coli M15 up to 10 uM by fluorescence based Stern-Volmer plot analysis | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 4. | ALA4269074 | F | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4269075 | F | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA4269076 | A | Cytotoxicity against human HEK293 cells assessed as cell viability up to 200 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4269077 | F | Induction of apoptosis in human MCF7 cells assessed as viable cells at IC50 after 24 to 48 hrs by Annexin V-FITC staining-based flow cytometric analysis relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4269078 | F | Induction of apoptosis in human MCF7 cells assessed as early apoptotic cells at IC50 after 24 to 48 hrs by Annexin V-FITC staining-based flow cytometric analysis (Rvb = 0%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4269079 | F | Induction of apoptosis in human MCF7 cells assessed as late apoptotic cells at IC50 after 24 to 48 hrs by Annexin V-FITC staining-based flow cytometric analysis (Rvb = 0%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4269080 | F | Induction of apoptosis in human MCF7 cells assessed as necrotic cells at IC50 after 24 to 48 hrs by Annexin V-FITC staining-based flow cytometric analysis (Rvb = 0%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4269081 | F | Induction of apoptosis in human HepG2 cells assessed as viable cells at IC50 after 24 to 48 hrs by Annexin V-FITC staining-based flow cytometric analysis relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA4269082 | F | Induction of apoptosis in human HepG2 cells assessed as early apoptotic cells at IC50 after 24 to 48 hrs by Annexin V-FITC staining-based flow cytometric analysis (Rvb = 0%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA4269083 | F | Induction of apoptosis in human HepG2 cells assessed as late apoptotic cells at IC50 after 24 to 48 hrs by Annexin V-FITC staining-based flow cytometric analysis (Rvb = 0%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA4269084 | F | Induction of apoptosis in human HepG2 cells assessed as necrotic cells at IC50 after 24 to 48 hrs by Annexin V-FITC staining-based flow cytometric analysis (Rvb = 0%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA4269085 | B | Inhibition of MARK4-mediated tau phosphorylation in human MCF7 cells at IC50 after 24 hrs by flow cytometric analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA4269086 | F | Induction of ROS generation in human MCF7 cells at IC50 after 5 to 6 hrs by DCFDA staining based flow cytometric analysis | Homo sapiens | 3 | cell-based format | Scientific Literature |
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