The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
The page will load shortly, Thanks for your patience!
# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4268905 A Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG addition measured after 2 hrs by TopCount method Homo sapiens 12 ALA4265969 cell-based format Scientific Literature 2. ALA4268906 B Inhibition of human kidneyl SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG addition measured after 2 hrs by TopCount method Homo sapiens 12 ALA4265969 cell-based format Scientific Literature 3. ALA4268909 A Metabolic stability in human liver microsomes at 1 uM after 10 mins in presence of NADPH Homo sapiens 15 ALA4265969 microsome format Scientific Literature 4. ALA4268910 A Metabolic stability in mouse liver microsomes at 1 uM after 10 mins in presence of NADPH Mus musculus 15 ALA4265969 microsome format Scientific Literature 5. ALA4268911 A Metabolic stability in rat liver microsomes at 1 uM after 10 mins in presence of NADPH Rattus norvegicus 15 ALA4265969 microsome format Scientific Literature 6. ALA4268912 A Half life in Sprague-Dawley rat at 2 mg/kg, iv Rattus norvegicus 3 ALA4265969 organism-based format Scientific Literature 7. ALA4268913 A Clearance in Sprague-Dawley rat at 2 mg/kg, iv Rattus norvegicus 3 ALA4265969 organism-based format Scientific Literature 8. ALA4268914 A Volume of distribution at steady state in Sprague-Dawley rat at 2 mg/kg, iv Rattus norvegicus 3 ALA4265969 organism-based format Scientific Literature 9. ALA4268915 A Half life in Sprague-Dawley rat at 10 mg/kg, po Rattus norvegicus 3 ALA4265969 organism-based format Scientific Literature 10. ALA4268916 A Cmax in Sprague-Dawley rat at 10 mg/kg, po Rattus norvegicus 3 ALA4265969 organism-based format Scientific Literature 11. ALA4268917 A Tmax in Sprague-Dawley rat at 10 mg/kg, po Rattus norvegicus 3 ALA4265969 organism-based format Scientific Literature 12. ALA4268918 A AUC (0 to infinity) in Sprague-Dawley rat at 10 mg/kg, po Rattus norvegicus 3 ALA4265969 organism-based format Scientific Literature 13. ALA4268919 A Oral bioavailability in Sprague-Dawley rat at 10 mg/kg Rattus norvegicus 3 ALA4265969 organism-based format Scientific Literature 14. ALA4268920 A Half life in cynomolgus monkey at 2 mg/kg, iv Macaca fascicularis 1 ALA4265969 organism-based format Scientific Literature 15. ALA4268921 A Clearance in cynomolgus monkey at 2 mg/kg, iv Macaca fascicularis 1 ALA4265969 organism-based format Scientific Literature 16. ALA4268922 A Volume of distribution at steady state in cynomolgus monkey at 2 mg/kg, iv Macaca fascicularis 1 ALA4265969 organism-based format Scientific Literature 17. ALA4268923 A Half life in cynomolgus monkey at 10 mg/kg, po Macaca fascicularis 1 ALA4265969 organism-based format Scientific Literature 18. ALA4268924 A Cmax in cynomolgus monkey at 10 mg/kg, po Macaca fascicularis 1 ALA4265969 organism-based format Scientific Literature 19. ALA4268925 A Tmax in cynomolgus monkey at 10 mg/kg, po Macaca fascicularis 1 ALA4265969 organism-based format Scientific Literature 20. ALA4268926 A AUC (0 to infinity) in cynomolgus monkey at 10 mg/kg, po Macaca fascicularis 1 ALA4265969 organism-based format Scientific Literature