# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4275989 | B | Inhibition of human IMPDH2 using IMP at 10 uM as substrate in presence of NAD+ after 30 mins relative to control | Homo sapiens | 38 | single protein format | Scientific Literature | ||
2. | ALA4275990 | B | Inhibition of human IMPDH2 using IMP as substrate in presence of NAD+ after 30 mins | Homo sapiens | 38 | single protein format | Scientific Literature | ||
3. | ALA4275991 | F | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
4. | ALA4275992 | F | Cytotoxicity against human DU145 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
5. | ALA4275993 | F | Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
6. | ALA4275994 | A | Cytotoxicity against mouse NIH/3T3 cells assessed as cell viability at 10 uM after 48 hrs by MTT assay relative to control | Mus musculus | 7 | cell-based format | Scientific Literature | ||
7. | ALA4275995 | A | Cytotoxicity against mouse NIH/3T3 cells assessed as cell viability at 100 uM after 48 hrs by MTT assay relative to control | Mus musculus | 7 | cell-based format | Scientific Literature | ||
8. | ALA4275996 | F | Potency index, ratio of mycophenolic acid IC50 to compound IC50 for cytotoxicity against human MDA-MB-231 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA4275997 | F | Potency index, ratio of mycophenolic acid IC50 to compound IC50 for cytotoxicity against human DU145 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA4276000 | P | Solubility in pH 7.4 sodium phosphate buffer after 2 hrs by HPLC analysis | 2 | small-molecule physicochemical format | Scientific Literature | |||
11. | ALA4276001 | P | Octanol-buffer partition coefficient, log D of the compound at pH 7.4 after 2 hrs by HPLC analysis | 2 | small-molecule physicochemical format | Scientific Literature | |||
12. | ALA4423275 | B | Inhibition of ABCG2 (unknown origin) expressed in MDCK II BCRP cells assessed as effect on pheophorbide A accumulation after 120 mins by flow cytometric analysis | Homo sapiens | 59 | cell-based format | Scientific Literature | ||
13. | ALA4423276 | B | Inhibition of ABCG2 (unknown origin) expressed in MDCK II BCRP cells assessed as effect on heophorbide A accumulation at 5 to 10 uM after 120 mins by flow cytometric analysis relative to control | Homo sapiens | 59 | cell-based format | Scientific Literature | ||
14. | ALA4423279 | B | Inhibition of ABCB1 in human A2780/ADR cells assessed as potentiation of daunorubicin-induced cytotoxicity measured after 72 hrs by MTT assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
15. | ALA4423280 | B | Inhibition of ABCG2 (unknown origin) expressed in MDCK2 cells co-expressing BCRP (unknown origin) assessed as potentiation of SN-38-induced cytotoxicity measured after 72 hrs by MTT assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
16. | ALA4423281 | A | Growth inhibition of human A2780 cells after 72 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
17. | ALA4423282 | A | Growth inhibition of human A2780/ADR cells after 72 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
18. | ALA4423283 | A | Growth inhibition of MDCK2 cells after 72 hrs by MTT assay | Canis lupus familiaris | 11 | cell-based format | Scientific Literature | ||
19. | ALA4423284 | A | Growth inhibition of MDCK2 cells expressing BCRP (unknown origin) after 72 hrs by MTT assay | Canis lupus familiaris | 11 | cell-based format | Scientific Literature | ||
20. | ALA4423285 | T | Therapeutic index, ratio of GI50 for human A2780/ADR cells to EC50 for ABCB1 in human A2780/ADR cells | Homo sapiens | 11 | cell-based format | Scientific Literature |