| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4253845 | B | Inhibition of trypsin (unknown origin) incubated for 30 mins using Abz-Thr-Pro-Arg-Ser-Ala-Leu-Gln-EDDnp substrate | Homo sapiens | 4 | ALA4251609 | protein format | Scientific Literature | |
| 2. | ALA4253846 | B | Inhibition of chymotrypsin (unknown origin) incubated for 30 mins using Abz-Thr-Pro-Phe-Ser-Gly-Gln-EDDnp substrate | Homo sapiens | 4 | ALA4251609 | assay format | Scientific Literature | |
| 3. | ALA4253847 | B | Inhibition of human neutrophil elastase incubated for 30 mins using Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-(3-NO2-Tyr) substrate | Homo sapiens | 4 | ALA4251609 | single protein format | Scientific Literature | |
| 4. | ALA4253848 | B | Inhibition of human recombinant MMP-2 expressed in CHO cells incubated for 30 mins by Mca-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp) substrate | Homo sapiens | 4 | ALA4251609 | cell-based format | Scientific Literature | |
| 5. | ALA4253849 | B | Inhibition of human cathepsin D incubated for 30 mins using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH2 substrate | Homo sapiens | 4 | ALA4251609 | single protein format | Scientific Literature | |
| 6. | ALA4253850 | B | Inhibition of human cathepsin H using fluorogenic AMC-derived peptide substrate assessed as reduction in residual activity preincubated for 30 mins followed by substrate addition | Homo sapiens | 4 | ALA4251609 | single protein format | Scientific Literature | |
| 7. | ALA4253851 | B | Inhibition of human cathepsin B | Homo sapiens | 4 | ALA4251609 | single protein format | Scientific Literature | |
| 8. | ALA4253863 | B | Substrate activity of trypsin (unknown origin) assessed as compound hydrolysis | Homo sapiens | 1 | ALA4251609 | protein format | Scientific Literature | |
| 9. | ALA4253864 | B | Substrate activity of human cathepsin B assessed as compound hydrolysis | Homo sapiens | 1 | ALA4251609 | single protein format | Scientific Literature | |
| 10. | ALA4253866 | B | Reversible inhibition of human cathepsin S at 20 uM preincubated for 30 mins followed by Biot-(PEG)2-Ahx-LeuValGly-DMK addition measured after 1 hr by chemiluminescence assay | Homo sapiens | 1 | ALA4251609 | single protein format | Scientific Literature | |
| 11. | ALA4253868 | B | Reversible inhibition of human cathepsin S at 20 uM in presence of excess Z-LR-AMC | Homo sapiens | 1 | ALA4251609 | single protein format | Scientific Literature | |
| 12. | ALA4253870 | B | Inhibition of human cathepsin K kinase activity at 3 uM pre-incubated for 30 mins before bradykinin substrate addition by reverse-phase chromatography | Homo sapiens | 1 | ALA4251609 | single protein format | Scientific Literature | |
| 13. | ALA4253871 | B | Inhibition of human cathepsin K kinase activity at 100 nM pre-incubated for 30 mins before bradykinin substrate addition by reverse-phase chromatography | Homo sapiens | 1 | ALA4251609 | single protein format | Scientific Literature | |
| 14. | ALA4253872 | B | Inhibition of human cathepsin K kinase activity at 3 uM pre-incubated for 30 mins before Abz-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-(3-NO2-Tyr) substrate addition by reverse-phase chromatography | Homo sapiens | 1 | ALA4251609 | single protein format | Scientific Literature | |
| 15. | ALA4253873 | B | Inhibition of human cathepsin K kinase activity at 100 nM pre-incubated for 30 mins before Abz-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-(3-NO2-Tyr) substrate addition by reverse-phase chromatography | Homo sapiens | 1 | ALA4251609 | single protein format | Scientific Literature | |
| 16. | ALA4253876 | B | Inhibition of human cathepsin K kinase activity assessed as normalized bradykinin equivalents ratio at 5 uM pre-incubated for 15 mins before bradykinin substrate addition by competitive enzyme immunoassay (Rvb = <0.5%) | Homo sapiens | 1 | ALA4251609 | single protein format | Scientific Literature | |
| 17. | ALA4253877 | B | Inhibition of human cathepsin K kinase activity assessed as normalized bradykinin equivalents ratio at 5 uM pre-incubated for 15 mins before kallidin substrate addition by competitive enzyme immunoassay (Rvb = <0.5%) | Homo sapiens | 1 | ALA4251609 | single protein format | Scientific Literature | |
| 18. | ALA4253880 | B | Reversible competitive inhibition of human cathepsin S using fluorogenic AMC-derived peptide substrate assessed as reduction in residual activity at pH 5.5 preincubated for 30 mins followed by substrate addition | Homo sapiens | 4 | ALA4251609 | single protein format | Scientific Literature | |
| 19. | ALA4253881 | B | Reversible competitive inhibition of human cathepsin S using fluorogenic AMC-derived peptide substrate assessed as reduction in residual activity at pH 7.4 preincubated for 30 mins followed by substrate addition | Homo sapiens | 4 | ALA4251609 | single protein format | Scientific Literature | |
| 20. | ALA4253882 | B | Reversible competitive inhibition of human cathepsin K using fluorogenic AMC-derived peptide substrate assessed as reduction in residual activity preincubated for 30 mins followed by substrate addition | Homo sapiens | 4 | ALA4251609 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!