# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4265253 | B | Displacement of [125I]-PYY(1 to 36 residues) from human Y1R expressed in BHK-21 cell membranes after 2 hrs by scintillation proximity assay | Homo sapiens | 43 | ALA4261636 | cell-based format | Scientific Literature | |
2. | ALA4265254 | B | Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assay | Homo sapiens | 43 | ALA4261636 | cell-based format | Scientific Literature | |
3. | ALA4265255 | B | Displacement of [125I]-PP from human Y4R expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay | Homo sapiens | 43 | ALA4261636 | cell-based format | Scientific Literature | |
4. | ALA4265256 | B | Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay | Homo sapiens | 43 | ALA4261636 | cell-based format | Scientific Literature | |
5. | ALA4265257 | F | Activation of human Y1R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 dye-based FLIPR assay | Homo sapiens | 20 | ALA4261636 | cell-based format | Scientific Literature | |
6. | ALA4265258 | F | Activation of human Y2R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 dye-based FLIPR assay | Homo sapiens | 20 | ALA4261636 | cell-based format | Scientific Literature | |
7. | ALA4265259 | F | Activation of human Y4R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 dye-based FLIPR assay | Homo sapiens | 20 | ALA4261636 | cell-based format | Scientific Literature | |
8. | ALA4265260 | F | Activation of human Y5R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 dye-based FLIPR assay | Homo sapiens | 20 | ALA4261636 | cell-based format | Scientific Literature | |
9. | ALA4265261 | B | Selectivity ratio of Ki for human Y1R expressed in BHK-21 cell membranes to Ki for human Y2R expressed in CHO cell membranes | Homo sapiens | 43 | ALA4261636 | cell-based format | Scientific Literature | |
10. | ALA4265262 | B | Selectivity ratio of Ki for human Y4R expressed in CHO-K1 cell membranes to Ki for human Y2R expressed in CHO cell membranes | Homo sapiens | 43 | ALA4261636 | cell-based format | Scientific Literature | |
11. | ALA4265263 | B | Selectivity ratio of Ki for human Y5R expressed in HEK293 cell membranes to Ki for human Y2R expressed in CHO cell membranes | Homo sapiens | 43 | ALA4261636 | cell-based format | Scientific Literature | |
12. | ALA4265268 | A | Drug metabolism in minipig plasma assessed as DDP-4-meditaed C-terminal cleavage by measuring half life at 1 uM by LC-MS analysis | Sus scrofa | 12 | ALA4261636 | single protein format | Scientific Literature |