| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4261855 | B | Inhibition of human DGAT2 | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 2. | ALA4261856 | A | Drug metabolism in human liver microsomes assessed as UGT-mediated glucuronidation by measuring clearance rate | Homo sapiens | 5 | microsome format | Scientific Literature | ||
| 3. | ALA4261857 | A | Drug metabolism in human liver microsomes assessed as CYP3A4-mediated oxidative metabolism by measuring clearance rate | Homo sapiens | 5 | microsome format | Scientific Literature | ||
| 4. | ALA4261858 | B | Inhibition of rat DGAT2 | Rattus norvegicus | 2 | single protein format | Scientific Literature | ||
| 5. | ALA4261859 | B | Inhibition of dog DGAT2 | Canis lupus familiaris | 2 | single protein format | Scientific Literature | ||
| 6. | ALA4261860 | B | Inhibition of MGAT1 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 7. | ALA4261861 | B | Inhibition of MGAT2 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 8. | ALA4261862 | B | Inhibition of MGAT3 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 9. | ALA4261863 | B | Inhibition of DGAT1 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 10. | ALA4261864 | A | Apparent intrinsic clearance in human hepatocytes assessed per million cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4261865 | A | Apparent intrinsic clearance in rat hepatocytes assessed per million cells | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4261866 | A | Apparent intrinsic clearance in dog hepatocytes assessed per million cells | Canis lupus familiaris | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4261867 | A | Drug metabolism in human liver microsomes assessed as fraction of UGT-mediated glucuronidation preincubated for 5 mins followed by addition of NADPH regenerating system and measured after 2.5 to 60 mins | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 14. | ALA4261868 | A | Drug metabolism in human liver microsomes assessed as fraction of CYP3A4-mediated oxidative metabolism preincubated for 5 mins followed by addition of NADPH regenerating system and measured after 2.5 to 60 mins | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 15. | ALA4261869 | A | Apparent permeability of the compound at pH 7.4 | 2 | assay format | Scientific Literature | |||
| 16. | ALA4261870 | P | Thermodynamic solubility of the compound at pH 6.5 | 2 | small-molecule physicochemical format | Scientific Literature | |||
| 17. | ALA4261871 | A | Fraction unbound in rat plasma | Rattus norvegicus | 2 | cell-free format | Scientific Literature | ||
| 18. | ALA4261872 | A | Fraction unbound in dog plasma | Canis lupus familiaris | 2 | cell-free format | Scientific Literature | ||
| 19. | ALA4261873 | A | Half life in beagle dog at 1 mg/kg, iv | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
| 20. | ALA4261874 | A | Half life in beagle dog at 5 mg/kg, po | Canis lupus familiaris | 2 | organism-based format | Scientific Literature |
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