| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4255695 | F | Cardioprotective activity against Langendorff isolated Sprague-Dawley rat heart ischemia-reperfusion injury model assessed as improvement in LVDP at 3 uM administered for 10 mins as infusion followed by 30 mins of global ischemia and 60 mins of reperfusion | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 2. | ALA4255696 | F | Cardioprotective activity against Langendorff isolated Sprague-Dawley rat heart ischemia-reperfusion injury model assessed as suppression of creatine kinase release at 3 uM administered for 10 mins as infusion followed by 30 mins of global ischemia and 60 mins of reperfusion | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 3. | ALA4255699 | F | Cardioprotective activity against Sprague-Dawley rat ischemia reperfusion-induced arrhythmia model assessed as ventricular fibrillation time at 1 mg/kg, iv administered 5 mins before ischemia (Rvb = 95.3 +/- 13 sec) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA4255700 | T | Toxicity in Sprague-Dawley rat ischemia reperfusion-induced arrhythmia model assessed as mortality at 1 mg/kg, iv administered 5 mins before ischemia (Rvb = 60%) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA4255701 | F | Cardioprotective activity against Sprague-Dawley rat ischemia reperfusion-induced arrhythmia model assessed as ventricular fibrillation time at 3 mg/kg, iv administered 5 mins before ischemia (Rvb = 95.3 +/- 13 sec) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA4255702 | F | Cardioprotective activity against Sprague-Dawley rat ischemia reperfusion-induced arrhythmia model assessed as ventricular fibrillation time at 3 mg/kg, iv administered 1 min before reperfusion (Rvb = 96.3 +/- 24.1 sec) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA4255703 | T | Toxicity in Sprague-Dawley rat ischemia reperfusion-induced arrhythmia model assessed as mortality at 3 mg/kg, iv administered 5 mins before ischemia (Rvb = 60%) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA4255704 | T | Toxicity in Sprague-Dawley rat ischemia reperfusion-induced arrhythmia model assessed as mortality at 3 mg/kg, iv administered 1 min before reperfusion (Rvb = 75%) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA4308114 | P | Aqueous solubility of compound in citrate-phosphate buffer at pH 7.0 after 30 mins by HPLC analysis | 3 | small-molecule physicochemical format | Scientific Literature |
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