# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4252097 | Binding | Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as substrate measured over 6 mins by spectrophotometric method | Trypanosoma | 17 | ALA4251554 | assay format | Scientific Literature | |
2. | ALA4252098 | Functional | Growth inhibition of Trypanosoma brucei brucei Lister 427 assessed as reduction in ATP levels after 48 hrs by CellTiter-Glo assay | Trypanosoma brucei brucei | 11 | ALA4251554 | organism-based format | Scientific Literature | |
3. | ALA4252100 | ADME | Cytotoxicity against human HepG2 cells after 96 hrs by CCK8 assay | Homo sapiens | 11 | ALA4251554 | cell-based format | Scientific Literature | |
4. | ALA4252101 | Toxicity | Selectivity index, ratio of CC50 for human HepG2 cells to IC50 for growth inhibition of Trypanosoma brucei brucei Lister 427 | 3 | ALA4251554 | assay format | Scientific Literature |