| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4271662 | B | Displacement of 1,8-ANS from FABP4 (unknown origin) after 3 mins by fluorescence assay | Homo sapiens | 37 | single protein format | Scientific Literature | ||
| 2. | ALA4271664 | A | Inhibition of FABP3 (unknown origin) | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 3. | ALA4271665 | B | Selectivity ratio of IC50 for FABP3 (unknown origin) to IC50 for displacement of 1,8-ANS from FABP4 (unknown origin) | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 4. | ALA4271671 | A | Cytotoxicity against mouse 3T3L1 pre-adipocytes assessed as cell death at 80 uM after 24 hrs by MTT assay relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4832570 | B | Displacement of 1,8-ANS from FABP4 (unknown origin) at 25 uM incubated for 3 mins by fluorescence based analysis relative to control | Homo sapiens | 30 | single protein format | Scientific Literature | ||
| 6. | ALA4832571 | B | Displacement of 1,8-ANS from FABP5 (unknown origin) at 25 uM incubated for 3 mins by fluorescence based analysis relative to control | Homo sapiens | 30 | single protein format | Scientific Literature | ||
| 7. | ALA4832572 | B | Displacement of 1,8-ANS from FABP4 (unknown origin) incubated for 3 mins by fluorescence based analysis | Homo sapiens | 30 | single protein format | Scientific Literature | ||
| 8. | ALA4832573 | B | Displacement of 1,8-ANS from FABP5 (unknown origin) incubated for 3 mins by fluorescence based analysis | Homo sapiens | 30 | single protein format | Scientific Literature | ||
| 9. | ALA4832574 | A | Displacement of 1,8-ANS from FABP3 (unknown origin) incubated for 3 mins by fluorescence based analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 10. | ALA4832575 | B | Selectivity ratio of IC50 for FABP3 (unknown origin) to IC50 for FABP4 (unknown origin) | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 11. | ALA4832576 | B | Selectivity ratio of IC50 for FABP3 (unknown origin) to IC50 for FABP5 (unknown origin) | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 12. | ALA4832579 | A | Half life in ICR mouse at 3 mg/kg, po measured for 24 hrs by LC-MS/MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 13. | ALA4832580 | A | Half life in ICR mouse at 1 mg/kg, iv measured for 24 hrs by LC-MS/MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 14. | ALA4832581 | A | Cmax in ICR mouse at 3 mg/kg, po and 1 mg/kg, iv measured for 24 hrs by LC-MS/MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 15. | ALA4832582 | A | AUC in ICR mouse at 3 mg/kg, po measured for 24 hrs by LC-MS/MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 16. | ALA4832583 | A | AUC in ICR mouse at 1 mg/kg, iv measured for 24 hrs by LC-MS/MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 17. | ALA4832584 | A | Clearance in ICR mouse at 3 mg/kg, po and 1 mg/kg, iv measured for 24 hrs by LC-MS/MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 18. | ALA4832585 | A | Oral bioavailability in ICR mouse at 3 mg/kg measured for 24 hrs by LC-MS/MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 19. | ALA4832586 | A | Cytotoxicity against human THP-1 cells assessed as reduction in cell viability at 50 uM incubated for 24 hrs by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 20. | ALA4832587 | F | Antiinflammatory activity against LPS-induced human THP-1 cells assessed as inhibition of MCP-1 gene expression at 25 uM incubated for 18 hrs followed by LPS-stimulation and measured after 6 hrs by qRT-PCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature |
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