| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4256853 | Functional | Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins followed by 5-oxo-ETE addition measured after 1 min by fluorescence assay | Homo sapiens | 18 | ALA4251757 | assay format | Scientific Literature | |
| 2. | ALA4256886 | ADME | Plasma concentration in cynomolgus monkey at 30 mg/kg administered via oral gavage after 3 days by RP-HPLC analysis | Macaca fascicularis | 2 | ALA4251757 | organism-based format | Scientific Literature | |
| 3. | ALA4256887 | ADME | Plasma concentration in cynomolgus monkey at 30 mg/kg administered via oral gavage after 7 days by RP-HPLC analysis | Macaca fascicularis | 2 | ALA4251757 | organism-based format | Scientific Literature | |
| 4. | ALA4256888 | ADME | Drug level in cynomolgus monkey plasma treated with 30 mg/kg 5-(5-Chloro-1-methyl-2-(6-phenylhexyl)-1H-indol-3-yl)-3-methyl-5-oxopentanoic Acid administered via oral gavage assessed as compound formation after 12 hrs by RP-HPLC analysis | Macaca fascicularis | 4 | ALA4251757 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!