| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4261074 | A | Half life in human liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured by LC/MS/MS analysis | Homo sapiens | 10 | ALA4257584 | microsome format | Scientific Literature | |
| 2. | ALA4261075 | A | Intrinsic clearance in human liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured after 45 mins by LC/MS/MS analysis | Homo sapiens | 10 | ALA4257584 | microsome format | Scientific Literature | |
| 3. | ALA4261076 | A | Hepatic clearance in human liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured after 45 mins by LC/MS/MS analysis | Homo sapiens | 10 | ALA4257584 | microsome format | Scientific Literature | |
| 4. | ALA4261077 | A | Intrinsic clearance in Sprague-Dawley rat liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured after 45 mins by LC/MS/MS analysis | Rattus norvegicus | 10 | ALA4257584 | microsome format | Scientific Literature | |
| 5. | ALA4261078 | A | Hepatic clearance in Sprague-Dawley rat liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured after 45 mins by LC/MS/MS analysis | Rattus norvegicus | 10 | ALA4257584 | microsome format | Scientific Literature | |
| 6. | ALA4261079 | A | Half life in Sprague-Dawley rat liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured by LC/MS/MS analysis | Rattus norvegicus | 10 | ALA4257584 | microsome format | Scientific Literature | |
| 7. | ALA4261080 | A | Intrinsic clearance in CD1 mouse liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured after 45 mins by LC/MS/MS analysis | Mus musculus | 10 | ALA4257584 | microsome format | Scientific Literature | |
| 8. | ALA4261081 | A | Hepatic clearance in CD1 mouse liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured after 45 mins by LC/MS/MS analysis | Mus musculus | 10 | ALA4257584 | microsome format | Scientific Literature | |
| 9. | ALA4261082 | A | Half life in CD1 mouse liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured by LC/MS/MS analysis | Mus musculus | 10 | ALA4257584 | microsome format | Scientific Literature | |
| 10. | ALA4261083 | A | Maximum plasma concentration in BALB/c mouse at 25 mg/kg, po via gavage by LC-MS analysis | Mus musculus | 10 | ALA4257584 | organism-based format | Scientific Literature | |
| 11. | ALA4261084 | A | Plasma concentration in BALB/c mouse assessed as time until the compound becomes undetectable at 25 mg/kg, po via gavage by LC-MS analysis | Mus musculus | 10 | ALA4257584 | organism-based format | Scientific Literature | |
| 12. | ALA4261085 | A | Drug uptake in BALB/c mouse heart at 25 mg/kg, po via gavage measured after 4 hrs post dose by LC-MS analysis | Mus musculus | 10 | ALA4257584 | organism-based format | Scientific Literature | |
| 13. | ALA4261086 | A | Drug uptake in BALB/c mouse lungs at 25 mg/kg, po via gavage measured after 4 hrs post dose by LC-MS analysis | Mus musculus | 10 | ALA4257584 | organism-based format | Scientific Literature | |
| 14. | ALA4261087 | A | Drug uptake in BALB/c mouse spleen at 25 mg/kg, po via gavage measured after 4 hrs post dose by LC-MS analysis | Mus musculus | 10 | ALA4257584 | organism-based format | Scientific Literature | |
| 15. | ALA4261088 | A | Drug uptake in BALB/c mouse blood at 25 mg/kg, po via gavage measured after 4 hrs post dose by LC-MS analysis | Mus musculus | 10 | ALA4257584 | organism-based format | Scientific Literature | |
| 16. | ALA4261089 | A | Drug uptake in BALB/c mouse brain at 25 mg/kg, po via gavage measured after 4 hrs post dose by LC-MS analysis | Mus musculus | 10 | ALA4257584 | organism-based format | Scientific Literature | |
| 17. | ALA4261090 | A | Drug uptake in BALB/c mouse liver at 25 mg/kg, po via gavage measured after 4 hrs post dose by LC-MS analysis | Mus musculus | 10 | ALA4257584 | organism-based format | Scientific Literature | |
| 18. | ALA4261091 | A | Drug uptake in BALB/c mouse heart at 25 mg/kg, po via gavage measured after 2 hrs post dose by LC-MS analysis | Mus musculus | 1 | ALA4257584 | organism-based format | Scientific Literature | |
| 19. | ALA4261092 | A | Drug uptake in BALB/c mouse liver at 25 mg/kg, po via gavage measured after 2 hrs post dose by LC-MS analysis | Mus musculus | 1 | ALA4257584 | organism-based format | Scientific Literature | |
| 20. | ALA4261093 | A | Drug uptake in BALB/c mouse lungs at 25 mg/kg, po via gavage measured after 2 hrs post dose by LC-MS analysis | Mus musculus | 1 | ALA4257584 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!