| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4258715 | B | Binding affinity to recombinant human CRK-2 nSH3 domain (1 to 304 residues) expressed in Escherichia coli by tryptophan fluorescence quenching assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 2. | ALA4258716 | B | Binding affinity to recombinant human CRK-2 nSH3 domain (1 to 304 residues) expressed in Escherichia coli at 25 degC by tryptophan fluorescence quenching assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 3. | ALA4258717 | B | Binding affinity to recombinant human CRK-2 nSH3 domain (1 to 304 residues) expressed in Escherichia coli by NMR analysis | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 4. | ALA4258718 | B | Ratio of Kd for recombinant human CRK-2 nSH3 domain (1 to 304 residues) expressed in Escherichia coli at 35 degC in presence of 1 M NaCl to Kd for recombinant human CRK-2 nSH3 domain (1 to 304 residues) expressed in Escherichia coli at 35 degC in presence of 80 mM NaCl | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 5. | ALA4258719 | B | Binding affinity to recombinant human CRK-2 nSH3 domain (1 to 304 residues) expressed in Escherichia coli assessed as inhibition of interaction with Abl by measuring Abl-mediated CRK-2 phosphorylation at Y221 residue at 1 uM after 10 to 30 mins by PAGE analysis (Rvb = 62%) | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 6. | ALA4258720 | B | Binding affinity to recombinant human CRK-2 nSH3 domain (1 to 304 residues) expressed in Escherichia coli assessed as inhibition of Abl T315I mutant-mediated CRK-2 phosphorylation at Y221 residue at 1 uM after 10 to 30 mins by PAGE analysis | Homo sapiens | 2 | assay format | Scientific Literature |
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