# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4265253 | Binding | Displacement of [125I]-PYY(1 to 36 residues) from human Y1R expressed in BHK-21 cell membranes after 2 hrs by scintillation proximity assay | Homo sapiens | 43 | ALA4261636 | cell-based format | Scientific Literature | |
2. | ALA4265254 | Binding | Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assay | Homo sapiens | 43 | ALA4261636 | cell-based format | Scientific Literature | |
3. | ALA4265255 | Binding | Displacement of [125I]-PP from human Y4R expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay | Homo sapiens | 43 | ALA4261636 | cell-based format | Scientific Literature | |
4. | ALA4265256 | Binding | Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay | Homo sapiens | 43 | ALA4261636 | cell-based format | Scientific Literature | |
5. | ALA4265257 | Functional | Activation of human Y1R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 dye-based FLIPR assay | Homo sapiens | 20 | ALA4261636 | cell-based format | Scientific Literature | |
6. | ALA4265258 | Functional | Activation of human Y2R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 dye-based FLIPR assay | Homo sapiens | 20 | ALA4261636 | cell-based format | Scientific Literature | |
7. | ALA4265259 | Functional | Activation of human Y4R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 dye-based FLIPR assay | Homo sapiens | 20 | ALA4261636 | cell-based format | Scientific Literature | |
8. | ALA4265260 | Functional | Activation of human Y5R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 dye-based FLIPR assay | Homo sapiens | 20 | ALA4261636 | cell-based format | Scientific Literature | |
9. | ALA4265261 | Binding | Selectivity ratio of Ki for human Y1R expressed in BHK-21 cell membranes to Ki for human Y2R expressed in CHO cell membranes | Homo sapiens | 43 | ALA4261636 | cell-based format | Scientific Literature | |
10. | ALA4265262 | Binding | Selectivity ratio of Ki for human Y4R expressed in CHO-K1 cell membranes to Ki for human Y2R expressed in CHO cell membranes | Homo sapiens | 43 | ALA4261636 | cell-based format | Scientific Literature | |
11. | ALA4265263 | Binding | Selectivity ratio of Ki for human Y5R expressed in HEK293 cell membranes to Ki for human Y2R expressed in CHO cell membranes | Homo sapiens | 43 | ALA4261636 | cell-based format | Scientific Literature | |
12. | ALA4265264 | ADME | Displacement of [125I]-PYY(1 to 36 residues) from mouse Y1R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay | Mus musculus | 7 | ALA4261636 | cell-based format | Scientific Literature | |
13. | ALA4265265 | Binding | Displacement of [125I]-PYY(1 to 36 residues) from mouse Y2R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay | Mus musculus | 7 | ALA4261636 | cell-based format | Scientific Literature | |
14. | ALA4265266 | ADME | Displacement of [125I]-PYY(1 to 36 residues) from mouse Y4R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay | Mus musculus | 7 | ALA4261636 | cell-based format | Scientific Literature | |
15. | ALA4265267 | Binding | Displacement of [125I]-PYY(1 to 36 residues) from mouse Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay | Mus musculus | 7 | ALA4261636 | cell-based format | Scientific Literature | |
16. | ALA4713464 | Functional | Agonist activity at human GLP-1R expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assay | Homo sapiens | 10 | ALA4706662 | cell-based format | Scientific Literature | |
17. | ALA4713465 | Functional | Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assay | Homo sapiens | 10 | ALA4706662 | cell-based format | Scientific Literature | |
18. | ALA4713466 | Functional | Agonist activity at human NPY1R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assay | Homo sapiens | 10 | ALA4706662 | cell-based format | Scientific Literature | |
19. | ALA4713467 | Functional | Agonist activity at rat glucagon receptor expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assay | Rattus norvegicus | 10 | ALA4706662 | cell-based format | Scientific Literature |
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