# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4267033 | B | Inhibition of full-length myc-tagged Plk1 C-terminal polo-box domain (unknown origin) assessed as inhibition of Plk1-Biotin-Ahx-PMQS(pT)PLN-NH2 peptide interaction preincubated for 1 hr followed by Biotin-Ahx-PMQS(pT)PLN-NH2 addition and measured after 1 hr by ELISA | Homo sapiens | 6 | single protein format | Scientific Literature | ||
2. | ALA4267034 | B | Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to Plk1 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition measured after 30 mins by fluorescence polarization assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
3. | ALA4267035 | B | Inhibition of 5CF-GPMQTSpTPKNG-NH2 binding to Plk2 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition measured after 30 mins by fluorescence polarization assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
4. | ALA4267036 | B | Inhibition of 5CF-PLATSpTPKNG-NH2 binding to Plk3 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition measured after 30 mins by fluorescence polarization assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
5. | ALA4267037 | B | Selectivity index, ratio of IC50 for Plk2 C-terminal polo-box domain (unknown origin) to IC50 for Plk1 C-terminal polo-box domain (unknown origin) | Homo sapiens | 5 | assay format | Scientific Literature | ||
6. | ALA4267038 | B | Selectivity index, ratio of IC50 for Plk3 C-terminal polo-box domain (unknown origin) to IC50 for Plk1 C-terminal polo-box domain (unknown origin) | Homo sapiens | 5 | assay format | Scientific Literature |