| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4253027 | B | Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPTLC analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 2. | ALA4253028 | A | Inhibition of human placental microsomal CYP19A1 at 2 uM using [1beta-3H]androstenedione after 21 mins by liquid scintillation spectrometry | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 3. | ALA4253029 | A | Half life in human liver S9 fraction at 1 uM up to 60 mins in presence of NADPH/UDPGA by LC-MS/MS analysis | Homo sapiens | 6 | subcellular format | Scientific Literature | ||
| 4. | ALA4253030 | A | Inhibition of human CYP17A1 expressed in Escherichia coli XL1 at 2 uM using [3H]-progesterone as substrate preincubated with substrate for 5 mins measured after 45 mins by HPLC analysis | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 5. | ALA4253031 | B | Inhibition of human 11beta-HSD1 expressed in HEK293 cell lysates at 200 uM using [1,2-3H]-cortisone as substrate preincubated for 10 mins followed by substrate addition in presence of NADPH by scintillation counting relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 6. | ALA4253033 | A | Half life in human plasma at 1 uM up to 150 mins by LC-MS/MS analysis | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
| 7. | ALA4253036 | A | Inhibition of human 11beta-HSD2 expressed in HEK293 cell lysates at 200 uM using [1,2,6,7-3H]-cortisol as substrate preincubated for 10 mins followed by substrate addition in presence of NAD by scintillation counting relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 8. | ALA4253037 | A | Cytotoxicity against human epidermal keratinocytes assessed as cell viability at 11 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA4253038 | T | Mutagenicity in Salmonella typhimurium TA7001/7002/7003/7004/7005/7006 up to 100 uM in presence of rat liver S9 fraction by Ames 2 assay | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA4253039 | T | Mutagenicity in Salmonella typhimurium TA7001/7002/7003/7004/7005/7006 up to 100 uM in absence of rat liver S9 fraction by Ames 2 assay | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4253040 | T | Mutagenicity in Salmonella typhimurium TA98 up to 100 uM in presence of rat liver S9 fraction by Ames 2 assay | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA4253041 | T | Mutagenicity in Salmonella typhimurium TA98 up to 100 uM in absence of rat liver S9 fraction by Ames 2 assay | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA4253042 | F | Induction of wound healing in human skin explant assessed as re-epithelialization at 5 uM administered topically for 3 days measured on day 1 post administration by hematoxylin-eosin-saffron staining based microscopic analysis (Rvb = 13 +/- 7%) | Homo sapiens | 1 | tissue-based format | Scientific Literature | ||
| 14. | ALA4253043 | F | Induction of wound healing in human skin explant assessed as re-epithelialization at 5 uM administered topically for 3 days measured on day 2 post administration by hematoxylin-eosin-saffron staining based microscopic analysis (Rvb = 28 +/- 2%) | Homo sapiens | 1 | tissue-based format | Scientific Literature | ||
| 15. | ALA4253044 | F | Induction of wound healing in human skin explant assessed as re-epithelialization at 5 uM administered topically for 3 days measured on day 3 post administration by hematoxylin-eosin-saffron staining based microscopic analysis relative to control | Homo sapiens | 1 | tissue-based format | Scientific Literature |
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