# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4257019 | B | Binding affinity to N-terminal GST tagged CNK PH domain (unknown origin) by SPR spectroscopy | Homo sapiens | 21 | ALA4257006 | assay format | Patent Bioactivity Data | |
2. | ALA4257022 | B | Competitive inhibition of CNK1 (unknown origin) binding to PIP3 (unknown origin) at 50 uM by SPR spectroscopy | Homo sapiens | 19 | ALA4257006 | assay format | Patent Bioactivity Data | |
3. | ALA4257037 | F | Antiproliferative activity against human NSCLC cells expressing mutant KRAS assessed as inhibition of 2D cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 15 | ALA4257006 | cell-based format | Patent Bioactivity Data | |
4. | ALA4257054 | F | Growth inhibition of human NCI-H1573 cells expressing wild type KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 7 | ALA4257006 | cell-based format | Patent Bioactivity Data | |
5. | ALA4257055 | B | Competitive inhibition of CNK1 (unknown origin) binding to PIP3 (unknown origin) by SPR spectroscopy | Homo sapiens | 3 | ALA4257006 | assay format | Patent Bioactivity Data | |
6. | ALA4419273 | F | Growth inhibition of human NCI-H1975 cells incubated for 3 days | Homo sapiens | 35 | ALA4419164 | cell-based format | Patent Bioactivity Data | |
7. | ALA4419274 | F | Growth inhibition of human NCI-H226 cells incubated for 3 days | Homo sapiens | 35 | ALA4419164 | cell-based format | Patent Bioactivity Data | |
8. | ALA4419287 | F | Growth inhibition of human A549 cells incubated for 3 days | Homo sapiens | 31 | ALA4419164 | cell-based format | Patent Bioactivity Data | |
9. | ALA4419288 | F | Growth inhibition of human NCI-H1373 cells incubated for 3 days | Homo sapiens | 31 | ALA4419164 | cell-based format | Patent Bioactivity Data | |
10. | ALA4419289 | B | Binding affinity to CNKSR1 PH-domain (unknown origin) assessed as binding RUmax by SPR spectroscopy | Homo sapiens | 31 | ALA4419164 | single protein format | Patent Bioactivity Data | |
11. | ALA4419290 | B | Binding affinity to CNKSR1 PH-domain (unknown origin) assessed as binding stability RUmax post injection by SPR spectroscopy | Homo sapiens | 32 | ALA4419164 | single protein format | Patent Bioactivity Data | |
12. | ALA4420449 | F | Growth inhibition of human NSCLC expressing mutant KRAS assessed as inhibition of 2D cell growth | Homo sapiens | 15 | ALA4420064 | cell-based format | Patent Bioactivity Data |