# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4256853 | Functional | Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins followed by 5-oxo-ETE addition measured after 1 min by fluorescence assay | Homo sapiens | 18 | ALA4251757 | assay format | Scientific Literature | |
2. | ALA4256857 | ADME | Tmax in cynomolgus monkey plasma at 30 mg/kg administered via oral gavage by RP-HPLC analysis | Macaca fascicularis | 6 | ALA4251757 | organism-based format | Scientific Literature | |
3. | ALA4256863 | ADME | Cmax in cynomolgus monkey plasma at 30 mg/kg administered via oral gavage by RP-HPLC analysis | Macaca fascicularis | 6 | ALA4251757 | organism-based format | Scientific Literature | |
4. | ALA4256869 | ADME | Half life in cynomolgus monkey plasma at 30 mg/kg administered via oral gavage by RP-HPLC analysis | Macaca fascicularis | 6 | ALA4251757 | organism-based format | Scientific Literature | |
5. | ALA4256875 | ADME | AUC (0 to 24 hrs) in cynomolgus monkey plasma at 30 mg/kg administered via oral gavage by RP-HPLC analysis | Macaca fascicularis | 6 | ALA4251757 | organism-based format | Scientific Literature | |
6. | ALA4256881 | ADME | Drug metabolism in cynomolgus monkey plasma at 30 mg/kg administered via oral gavage assessed as phenylpentamethylene side chain modification after 12 hrs by RP-HPLC analysis | Macaca fascicularis | 1 | ALA4251757 | organism-based format | Scientific Literature |