# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4263118 | F | Reactivation of latent HIV1 LTR-GFP infected in human Jurkat-Lat A10.6 cells assessed as increase in GFP-positive cells after 24 hrs by flow cytometry relative to control | Human immunodeficiency virus 1 | 6 | ALA4261560 | organism-based format | Scientific Literature | |
2. | ALA4263119 | A | Cytotoxicity against human J-Lat cells | Homo sapiens | 4 | ALA4261560 | cell-based format | Scientific Literature | |
3. | ALA4263121 | F | Reactivation of latent HIV1 LTR-GFP infected in human Jurkat-Lat A10.6 cells assessed as GFP-positive cells at 10 uM after 24 hrs by flow cytometry (Rvb = 5.06%) | Human immunodeficiency virus 1 | 1 | ALA4261560 | organism-based format | Scientific Literature | |
4. | ALA4263122 | F | Reactivation of latent HIV1 LTR-GFP infected in human Jurkat-Lat A10.6 cells assessed as GFP-positive cells at 100 uM after 24 hrs by flow cytometry (Rvb = 5.06%) | Human immunodeficiency virus 1 | 1 | ALA4261560 | organism-based format | Scientific Literature | |
5. | ALA4263124 | A | Cytotoxicity against PBMC (unknown origin) assessed as reduction in cell viability up to 500 uM by CCK8 assay | Not specified | 1 | ALA4261560 | cell-based format | Scientific Literature | |
6. | ALA4263125 | F | Reactivation of Simian immunodeficiency virus mac239 latent provirus in primary CD4+ T lymphocytes isolated from infected rhesus monkey PBMC assessed as increase in msRNA level after 24 hrs by RT-PCR analysis | Simian immunodeficiency virus | 2 | ALA4261560 | organism-based format | Scientific Literature | |
7. | ALA4263126 | F | Reactivation of Simian immunodeficiency virus mac239 latent provirus in primary CD4+ T lymphocytes isolated from infected rhesus monkey PBMC assessed as increase in usRNA level after 24 hrs by RT-PCR analysis | Simian immunodeficiency virus | 2 | ALA4261560 | organism-based format | Scientific Literature | |
8. | ALA4263127 | F | Reactivation of HIV latent provirus in primary CD4+ T lymphocytes isolated from infected human PBMC assessed as increase in msRNA level at 10 to 100 uM after 24 hrs by RT-PCR analysis | Human immunodeficiency virus | 1 | ALA4261560 | organism-based format | Scientific Literature | |
9. | ALA4263128 | F | Reactivation of HIV latent provirus in primary CD4+ T lymphocytes isolated from infected human PBMC assessed as increase in usRNA level at 10 to 100 uM after 24 hrs by RT-PCR analysis | Human immunodeficiency virus | 1 | ALA4261560 | organism-based format | Scientific Literature | |
10. | ALA4263131 | A | Induction of monkey PBMC CD4+ T cells activation assessed as increase in CD25 expression up to 500 uM after 24 hrs by flow cytometry | Macaca mulatta | 1 | ALA4261560 | cell-based format | Scientific Literature | |
11. | ALA4263132 | A | Induction of monkey PBMC CD4+ T cells activation assessed as increase in CD69 expression up to 500 uM after 24 hrs by flow cytometry | Macaca mulatta | 1 | ALA4261560 | cell-based format | Scientific Literature | |
12. | ALA4263133 | A | Induction of monkey PBMC CD4+ T cells activation assessed as increase in CCR5 expression up to 500 uM after 24 hrs by flow cytometry | Macaca mulatta | 1 | ALA4261560 | cell-based format | Scientific Literature | |
13. | ALA4263134 | A | Induction of monkey PBMC CD3+ T cells activation assessed as increase in CD25 expression up to 500 uM after 24 hrs by flow cytometry | Macaca mulatta | 1 | ALA4261560 | cell-based format | Scientific Literature | |
14. | ALA4263135 | A | Induction of monkey PBMC CD3+ T cells activation assessed as increase in CD69 expression up to 500 uM after 24 hrs by flow cytometry | Macaca mulatta | 1 | ALA4261560 | cell-based format | Scientific Literature | |
15. | ALA4263136 | A | Induction of monkey PBMC CD3+ T cells activation assessed as increase in CCR5 expression up to 500 uM after 24 hrs by flow cytometry | Macaca mulatta | 1 | ALA4261560 | cell-based format | Scientific Literature |
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