| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4260920 | B | Stabilization of SMN2 mRNA in mouse myoblasts assessed as increase in SMN protein level by ELISA relative to DMSO control | Mus musculus | 22 | assay format | Scientific Literature | ||
| 2. | ALA4260921 | B | Stabilization of SMN2 mRNA in mouse myoblasts assessed as increase in SMN protein level by ELISA | Mus musculus | 21 | assay format | Scientific Literature | ||
| 3. | ALA4260922 | P | Lipophilicity, log D of the compound at pH 7.4 | 18 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA4260925 | B | Displacement of [3H]-dofetilide from human ERG expressed in CHO cell membranes after 90 mins by micro-beta counting | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 5. | ALA4260939 | A | Permeability of the compound at 5 uM after 4 hrs by PAMPA | 7 | assay format | Scientific Literature | |||
| 6. | ALA4260940 | A | Efflux ratio of permeability in MDCK cells expressing human MDR1 | Canis lupus familiaris | 5 | cell-based format | Scientific Literature | ||
| 7. | ALA4260941 | A | Clearance in Sprague-Dawley rat at 1 mg/kg, iv or 10 mg/kg, po | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 8. | ALA4260942 | A | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 9. | ALA4260943 | A | AUC in Sprague-Dawley rat at 1 mg/kg, iv or 10 mg/kg, po | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 10. | ALA4260944 | A | Drug level in Sprague-Dawley rat brain at 1 mg/kg, iv or 10 mg/kg, po after 7 hrs | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 11. | ALA4260945 | A | Protein binding rat plasma | Rattus norvegicus | 4 | cell-free format | Scientific Literature | ||
| 12. | ALA4260947 | F | In-vivo stabilization SMN2 mRNA in SMN C/+ mouse model assessed as increase in SMN protein levels at 30 mg/kg, po after 5 days | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 13. | ALA4382894 | B | Modulation of full length SMN2 mRNA (unknown origin) splicing by luciferase reporter gene assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA5237930 | B | Modulation of human SMN2 level in NSC34 cells by ELISA | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 15. | ALA5237931 | B | Modulation of human SMN2 level in NSC34 cells assessed as fold change by ELISA | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 16. | ALA5237932 | T | Inhibition of hERG | Homo sapiens | 6 | assay format | Scientific Literature |
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