# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4261728 | F | Neuroprotective activity against glutamate-induced excitotoxicity in mouse primary cerebellar granule neurons assessed as increase in cell viability at 1 uM preincubated for 2 hrs followed by glutamate challenge measured after 24 hrs by MTT assay | Mus musculus | 9 | assay format | Scientific Literature | ||
2. | ALA4261731 | F | Neuroprotective activity against glutamate-induced excitotoxicity in mouse primary cerebellar granule neurons assessed as increase in cell viability preincubated for 2 hrs followed by glutamate challenge measured after 24 hrs by MTT assay | Mus musculus | 17 | assay format | Scientific Literature | ||
3. | ALA4261732 | F | Vasodilating activity in Sprague-Dawley rat aortic ring precontracted with phenylephrine in absence of endothelium | Rattus norvegicus | 8 | tissue-based format | Scientific Literature | ||
4. | ALA4261733 | F | Vasodilating activity in Sprague-Dawley rat aortic ring precontracted with phenylephrine in presence of endothelium | Rattus norvegicus | 8 | tissue-based format | Scientific Literature | ||
5. | ALA4261734 | F | Neuroprotective activity against glutamate-induced neuronal damage in rat cortical neurons assessed as increase in cell viability preincubated for 2 hrs followed by glutamate challenge measured after 24 hrs by MTT assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
6. | ALA4261735 | F | Neuroprotective activity against glutamate-induced neuronal damage in rat cortical neurons assessed as increase in cell viability preincubated for 2 hrs followed by glutamate challenge measured after 24 hrs by FAD/propidium iodide staining-based inverted fluorescence microscopic method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
7. | ALA4261737 | F | Neuroprotective activity against glutamate-induced neuronal damage in rat cortical neurons assessed as decrease in intracellular calcium influx at 15 uM preincubated for 5 min followed by glutamate challenge measured over 280 secs by Fluo-3/AM dye-based fluorescence assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
8. | ALA4261739 | F | Neuroprotective activity against glutamate-induced neuronal damage in rat cortical neurons assessed as decrease in H2O2 formation preincubated for 2 hrs followed by glutamate challenge measured after 12 hrs by H2DCF-DA dye-based fluorescence assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
9. | ALA4261740 | F | Neuroprotective activity against glutamate-induced neuronal damage in rat cortical neurons assessed as decrease in formation of hydroxy radicals preincubated for 2 hrs followed by glutamate challenge measured after 12 hrs by HPF dye-based fluorescence assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
10. | ALA4261741 | F | Neuroprotective activity against glutamate-induced neuronal damage in rat cortical neurons assessed as decrease in formation of superoxide anions preincubated for 2 hrs followed by glutamate challenge measured after 12 hrs by DHE dye-based fluorescence assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
11. | ALA4261742 | F | Neuroprotective activity against glutamate-induced neuronal damage in rat cortical neurons assessed as decrease in formation of nitric oxide preincubated for 2 hrs followed by glutamate challenge measured after 12 hrs by DAF-FM dye-based fluorescence assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
12. | ALA4261743 | F | Neuroprotective activity against glutamate-induced neuronal damage in rat cortical neurons assessed as decrease in formation of peroxynitrite preincubated for 2 hrs followed by glutamate challenge measured after 12 hrs by DHR123 dye-based fluorescence assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
13. | ALA4261749 | F | Neuroprotective activity in rat cortical neurons assessed as inhibition of glutamate-induced decrease in mitochondrial membrane potential at 5 to 45 uM preincubated for 2 hrs followed by glutamate challenge measured after 12 hrs by JC1 staining-based fluorescence assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature |