# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4269815 | F | Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 24 hrs by cellTiter-Glo reagent based assay | Homo sapiens | 7 | ALA4266022 | cell-based format | Scientific Literature | |
2. | ALA4269816 | B | Inhibition of NF-kappaB in human MDA-MB-231 cells assessed as reduction in TNFalpha-induced NO production incubated with compound for 20 mins followed by TNFalpha stimulation measured after 2 hrs by luminescence assay | Homo sapiens | 7 | ALA4266022 | cell-based format | Scientific Literature | |
3. | ALA4269818 | F | Inhibition of cell migration in human MDA-MB-231 cells at 5 uM after 24 hrs by wound-scratch assay | Homo sapiens | 3 | ALA4266022 | cell-based format | Scientific Literature | |
4. | ALA4269819 | F | Inhibition of cell migration in human MDA-MB-231 cells at 10 uM after 24 hrs by wound-scratch assay | Homo sapiens | 3 | ALA4266022 | cell-based format | Scientific Literature | |
5. | ALA4269820 | F | Anti-invasive activity in human MDA-MB-231 cells assessed as inhibition of cell invasion into surrounding extracellular matrix at 10 uM after 24 hrs | Homo sapiens | 1 | ALA4266022 | cell-based format | Scientific Literature | |
6. | ALA4627631 | F | Induction of DNA damage in human SU8686 cells assessed as increase in gammaH2AX phosphorylation at ser193 at cytotoxic IC50 incubated for 24 hrs by fluorometry method | Homo sapiens | 17 | ALA4627257 | cell-based format | Scientific Literature | |
7. | ALA4627638 | F | Induction of DNA damage in human SU8686 cells assessed as tail DNA formation at IC50 by alkaline Comet assay | Homo sapiens | 10 | ALA4627257 | cell-based format | Scientific Literature | |
8. | ALA4627639 | F | Induction of DNA damage in human SU8686 cells assessed as increase gammaH2AX protein level at IC50 for 24 hrs in presence of 5 uM cisplatin by western blot analysis | Homo sapiens | 7 | ALA4627257 | cell-based format | Scientific Literature |